Yi Kyu-Ho, Lee Siyun, Lee Ji-Hyun, Lee Hyung-Jin
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOURProject, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seoul 03722, Republic of Korea.
Maylin Clinic (Apgujeong), Seoul 07335, Republic of Korea.
Diagnostics (Basel). 2023 Sep 20;13(18):3005. doi: 10.3390/diagnostics13183005.
Histological and naked-eye dissections are frequently used to investigate human anatomy. However, limitations of conventional methods include tissue damage and difficulty in observing structures, rendering findings limited. Micro-computed tomography (micro-CT) allows for a three-dimensional observation with whole-mount staining for contrast enhancement. A precise anatomical understanding of the larynx is essential for both the medical and surgical fields; however, the larynx is difficult to dissect because of its minuscule and complex structures. Therefore, we aimed to clarify the detailed anatomy of the larynx using micro-CT. The study was conducted on twelve specimens of cadavers using Lugol-based-contrast micro-CT. Using Lugol-micro-CT, relevant information on human structures was obtained. Consequently, we successfully employed the Lugol-micro-CT technique in the analysis of specific human soft tissue structures that are challenging to analyze using conventional methods.
组织学和肉眼解剖常用于研究人体解剖结构。然而，传统方法的局限性包括组织损伤以及观察结构的困难，这使得研究结果有限。微计算机断层扫描（micro-CT）可通过整体染色进行三维观察以增强对比度。精确了解喉部的解剖结构对医学和外科领域都至关重要；然而，由于喉部结构微小且复杂，很难进行解剖。因此，我们旨在使用micro-CT阐明喉部的详细解剖结构。本研究使用基于卢戈氏碘液对比的micro-CT对12具尸体标本进行了研究。通过卢戈氏碘液micro-CT，获得了有关人体结构的相关信息。因此，我们成功地将卢戈氏碘液micro-CT技术应用于分析特定的人体软组织结构，而这些结构使用传统方法进行分析具有挑战性。
