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本文引用的文献

1
Hearing Loss in Children: A Review.儿童听力损失:综述。
JAMA. 2020 Dec 1;324(21):2195-2205. doi: 10.1001/jama.2020.17647.
2
Genomic analysis of inherited hearing loss in the Palestinian population.巴勒斯坦人群遗传性听力损失的基因组分析。
Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20070-20076. doi: 10.1073/pnas.2009628117. Epub 2020 Aug 3.
3
The Beginning of Life Issues: An Islamic Perspective.生命起始问题:伊斯兰教视角
J Relig Health. 2021 Apr;60(2):663-683. doi: 10.1007/s10943-020-01018-3.
4
Cochlear Implantation in Children with Usher's Syndrome: A South Asian Experience.患有乌舍尔综合征儿童的人工耳蜗植入:南亚经验
Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):140-144. doi: 10.1007/s12070-019-01759-y. Epub 2019 Nov 7.
5
[INNOVATIONS IN RESEARCH OF HEREDITARY DEAFNESS].[遗传性耳聋的研究创新]
Harefuah. 2020 Feb;159(1):117-122.
6
Genetic Epidemiology of Hearing Loss in the 22 Arab Countries: A Systematic Review.22 个阿拉伯国家听力损失的遗传流行病学:系统评价。
Otol Neurotol. 2020 Feb;41(2):e152-e162. doi: 10.1097/MAO.0000000000002489.
7
Genetic disorder prenatal diagnosis and pregnancy termination practices among high consanguinity population, Saudi Arabia.高近亲结婚人群中的遗传疾病产前诊断和妊娠终止实践,沙特阿拉伯。
Sci Rep. 2019 Nov 21;9(1):17248. doi: 10.1038/s41598-019-53655-8.
8
Identification of novel microsatellite markers flanking GJB2 gene in order to use in preimplantation genetic diagnosis of hearing loss: A comparison of whole-genome amplification and semi-nested PCR.鉴定GJB2基因侧翼的新型微卫星标记物以用于听力损失的植入前基因诊断:全基因组扩增与半巢式PCR的比较
Eur J Med Genet. 2020 Apr;63(4):103796. doi: 10.1016/j.ejmg.2019.103796. Epub 2019 Oct 25.
9
Autosomal recessive diseases among the Israeli Arabs.以色列阿拉伯人的常染色体隐性遗传病。
Hum Genet. 2019 Oct;138(10):1117-1122. doi: 10.1007/s00439-019-02043-3. Epub 2019 Jun 26.
10
Assessing and monitoring the impact of the national newborn hearing screening program in Israel.评估和监测以色列全国新生儿听力筛查项目的影响。
Isr J Health Policy Res. 2019 Mar 11;8(1):30. doi: 10.1186/s13584-019-0296-6.

以色列犹太和穆斯林妇女怀有失聪胎儿时的产前诊断与终止妊娠情况

Prenatal Diagnosis and Pregnancy Termination in Jewish and Muslim Women with a Deaf Child in Israel.

作者信息

Amiel Aliza, Na'amnih Wasef, Tarabeih Mahdi

机构信息

School of Nursing Science, The Academic College of Tel Aviv-Yaffo, Tel Aviv 64044, Israel.

Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

出版信息

Children (Basel). 2023 Aug 23;10(9):1438. doi: 10.3390/children10091438.

DOI:10.3390/children10091438
PMID:37761399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10528870/
Abstract

Deafness is the most common sensory disability in humans, influencing all aspects of life, However, early diagnosis of hearing impairment and initiating the rehabilitation process are of great importance to enable the development of language and communication as soon as possible. We examined the differences in attitudes towards performing prenatal invasive tests and pregnancy terminations in Jewish and Muslim women in Israel due to deafness. Overall, 953 Israeli women, aged 18-46 years with a mean age of 32.0 (SD = 7.12), were enrolled. Of those, 68.7% were city dwellers and 31.3% were village dwellers, and 60.2% were Muslim women and 39.8% were Jewish women. All participants had a child with a hearing impairment or deafness. The group with no genetic hearing loss performed more prenatal invasive tests and pregnancy terminations than those with genetic hearing loss in both ethnic groups. Jewish women performed more invasive prenatal tests and, consequently, a pregnancy termination. Secular Jewish women more frequently underwent pregnancy terminations due to fetal deafness. Further genetic counseling and information concerning IVF and PGD procedures should be provided to the Muslim population.

摘要

耳聋是人类最常见的感官残疾,影响生活的方方面面。然而,早期诊断听力障碍并启动康复过程对于尽快促进语言和沟通发展至关重要。我们研究了以色列犹太和穆斯林女性因耳聋而对进行产前侵入性检查和终止妊娠的态度差异。总共招募了953名年龄在18至46岁之间、平均年龄为32.0岁(标准差=7.12)的以色列女性。其中,68.7%是城市居民,31.3%是农村居民,60.2%是穆斯林女性,39.8%是犹太女性。所有参与者都有一个患有听力障碍或耳聋的孩子。在两个族群中,无遗传性听力损失的组比有遗传性听力损失的组进行了更多的产前侵入性检查和终止妊娠。犹太女性进行了更多的侵入性产前检查,因此终止妊娠的比例更高。世俗犹太女性因胎儿耳聋而更频繁地终止妊娠。应该向穆斯林人群提供进一步的遗传咨询以及有关体外受精和植入前基因诊断程序的信息。