Suppr超能文献

沙特阿拉伯利雅得多专科医院重症监护病房收治的新冠肺炎患者特征:一项回顾性研究

Characteristics of COVID-19 Patients Admitted to Intensive Care Unit in Multispecialty Hospital of Riyadh, Saudi Arabia: A Retrospective Study.

作者信息

Almuqbil Mansour, Almoteer Ali Ibrahim, Suwayyid Alwaleed Mohammed, Bakarman Abdulaziz Hussain, Alrashed Raed Fawaz, Alrobish Majed, Alasalb Fahad, Alhusaynan Abdulaziz Abdulrahman, Alnefaie Mohammed Hadi, Altayar Abdullah Saud, Alobid Saad Ebrahim, Almadani Moneer E, Alshehri Ahmed, Alghamdi Adel, Asdaq Syed Mohammed Basheeruddin

机构信息

Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

Department of Pharmacy Practice, College of Pharmacy, AlMaarefa University, Dariyah, Riyadh 13713, Saudi Arabia.

出版信息

Healthcare (Basel). 2023 Sep 8;11(18):2500. doi: 10.3390/healthcare11182500.

Abstract

During the early stages of the COVID-19 pandemic, infection rates were high and symptoms were severe. Medical resources, including healthcare experts and hospital facilities, were put to the test to ensure their readiness to deal with this unique event. An intensive care unit (ICU) is expected to be required by many hospitalized patients. Many hospitals worldwide lacked resources during the pandemic's peak stages, particularly in critical care treatment. Because of this, there were issues with capacity, as well as an excessive influx of patients. Additionally, even though the research location provides medical care to a sizable population, there is a paucity of scientific data detailing the situation as it pertains to COVID-19 patients during the height of the outbreak. Therefore, this study aimed to identify and describe the features of COVID-19 patients hospitalized in the ICU of one of the multispecialty hospitals in Riyadh, Saudi Arabia. An observational retrospective study was conducted using a chart review of COVID-19 patients admitted to the ICU between March 2020 and December 2020. To characterize the patients, descriptive statistics were utilized. An exploratory multivariate regression analysis was carried out on the study cohort to investigate the factors that were shown to be predictors of death and intubation. Only 333 (29.33%) of the 1135 samples from the hospital's medical records were used for the final analysis and interpretation. More than 76% of the patients in the study were male, with a mean BMI of 22.07 and an average age of around 49 years. The most frequent chronic condition found among the patients who participated in the study was diabetes (39.34%), followed by hypertension (31.53%). At the time of admission, 63 of the total 333 patients needed to have intubation performed. In total, 22 of the 333 patients died while undergoing therapy. People with both diabetes and hypertension had a 7.85-fold higher risk of death, whereas those with only diabetes or hypertension had a 5.43-fold and 4.21-fold higher risk of death, respectively. At admission, intubation was necessary for many male patients (49 out of 63). Most intubated patients had hypertension, diabetes, or both conditions. Only 13 of the 63 patients who had been intubated died, with the vast majority being extubated. Diabetes and hypertension were significant contributors to the severity of illness experienced by COVID-19 participants. The presence of multiple comorbidities had the highest risk for intubation and mortality among ICU-admitted patients. Although more intubated patients died, the fatality rate was lower than in other countries due to enhanced healthcare management at the ICU of the study center. However, large-scale trials are needed to determine how effective various strategies were in preventing ICU admission, intubation, and death rates.

摘要

在新冠疫情的早期阶段,感染率很高且症状严重。包括医疗专家和医院设施在内的医疗资源面临考验,以确保它们有能力应对这一特殊事件。预计许多住院患者将需要重症监护病房(ICU)。在疫情高峰期,全球许多医院都缺乏资源,尤其是在重症治疗方面。因此,出现了容量问题以及患者大量涌入的情况。此外,尽管研究地点为大量人群提供医疗服务,但在疫情高峰期,关于新冠患者情况的科学数据却很匮乏。因此,本研究旨在识别和描述沙特阿拉伯利雅得一家多专科医院ICU中新冠住院患者的特征。通过对2020年3月至2020年12月期间入住ICU的新冠患者病历进行回顾,开展了一项观察性回顾性研究。为描述患者特征,采用了描述性统计方法。对研究队列进行了探索性多变量回归分析,以调查显示为死亡和插管预测因素的因素。医院病历中的1135个样本中,只有333个(29.33%)用于最终分析和解读。研究中超过76%的患者为男性,平均BMI为22.07,平均年龄约49岁。参与研究的患者中最常见的慢性病是糖尿病(39.34%),其次是高血压(31.53%)。在入院时,333名患者中有63名需要进行插管。在接受治疗期间,333名患者中有22名死亡。同时患有糖尿病和高血压的患者死亡风险高7.85倍,而仅患有糖尿病或高血压的患者死亡风险分别高5.43倍和4.21倍。入院时,许多男性患者(63名中的49名)需要插管。大多数插管患者患有高血压、糖尿病或两种疾病都有。63名插管患者中只有13名死亡,绝大多数患者成功拔管。糖尿病和高血压是新冠患者病情严重程度的重要因素。多种合并症的存在在入住ICU的患者中插管和死亡风险最高。尽管插管患者死亡人数更多,但由于研究中心ICU加强了医疗管理,死亡率低于其他国家。然而,需要进行大规模试验来确定各种策略在预防ICU入院、插管和死亡率方面的效果如何。

相似文献

9
Diabetes and Covid-19 among hospitalized patients in Saudi Arabia: a single-centre retrospective study.
Cardiovasc Diabetol. 2020 Dec 5;19(1):205. doi: 10.1186/s12933-020-01184-4.
10
Comorbidities and Risk Factors for Severe Outcomes in COVID-19 Patients in Saudi Arabia: A Retrospective Cohort Study.
J Multidiscip Healthc. 2021 Aug 12;14:2169-2183. doi: 10.2147/JMDH.S317884. eCollection 2021.

引用本文的文献

本文引用的文献

4
A Systematic Review on the Safety and Efficacy of COVID-19 Vaccines Approved in Saudi Arabia.
Vaccines (Basel). 2023 Jan 28;11(2):281. doi: 10.3390/vaccines11020281.
7
Impact of COVID-19 vaccination on the risk of developing long-COVID and on existing long-COVID symptoms: A systematic review.
EClinicalMedicine. 2022 Aug 27;53:101624. doi: 10.1016/j.eclinm.2022.101624. eCollection 2022 Nov.
8
COVID-19 and Acute Kidney Injury.
Crit Care Clin. 2022 Jul;38(3):473-489. doi: 10.1016/j.ccc.2022.01.002. Epub 2022 Jan 10.
10
Risk and Protective Factors for COVID-19 Morbidity, Severity, and Mortality.
Clin Rev Allergy Immunol. 2023 Feb;64(1):90-107. doi: 10.1007/s12016-022-08921-5. Epub 2022 Jan 19.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验