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全人群中眼眶斑块旋切术的安全性和有效性:下西里西亚眼眶斑块旋切术登记处(LOAR)的中期结果

Safety and Efficacy of Orbital Atherectomy in the All-Comer Population: Mid-Term Results of the Lower Silesian Orbital Atherectomy Registry (LOAR).

作者信息

Rola Piotr, Włodarczak Szymon, Barycki Mateusz, Furtan Łukasz, Jastrzębski Artur, Kędzierska Michalina, Doroszko Adrian, Lesiak Maciej, Włodarczak Adrian

机构信息

Faculty of Health Sciences and Physical Culture, Witelon Collegium State University, 59-220 Legnica, Poland.

Department of Cardiology, Provincial Specialized Hospital, 59-220 Legnica, Poland.

出版信息

J Clin Med. 2023 Sep 8;12(18):5842. doi: 10.3390/jcm12185842.

DOI:10.3390/jcm12185842
PMID:37762782
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10532293/
Abstract

BACKGROUND

Coronary calcifications represent a challenging subset for the interventional cardiologist performing percutaneous coronary intervention (PCI) and are well-established risk factors for adverse outcomes. Adequate plaque modification prior to stent implantation is critical to achieve an optimal outcome following PCI. Recently, a novel orbital atherectomy device has been introduced into clinical practice to modify calcified plaques. We evaluated the mid-term safety and efficacy of OA in a high-risk "all-comers" population.

METHODS

We evaluated 96 consecutive patients with severely calcified coronary lesions who underwent PCI facilitated by the orbital atherectomy device.

RESULTS

In-hospital MACCE was 5.2% without target lesion revascularization. At 6-month follow-up, the MACCE rate was 10.4% with a concomitant TLR rate of 1%.

CONCLUSIONS

Our mid-term data showed good safety and efficacy of orbital atherectomy as a plaque-modifying tool in an all-comers cohort with severely calcified coronary lesions.

摘要

背景

冠状动脉钙化对于进行经皮冠状动脉介入治疗(PCI)的介入心脏病学家而言是一个具有挑战性的亚组,并且是不良结局的公认危险因素。在支架植入前进行充分的斑块修饰对于PCI术后获得最佳结局至关重要。最近,一种新型的轨道旋磨术设备已被引入临床实践以修饰钙化斑块。我们评估了轨道旋磨术在高危“所有患者”人群中的中期安全性和有效性。

方法

我们评估了96例连续接受轨道旋磨术设备辅助PCI的严重钙化冠状动脉病变患者。

结果

住院期间主要不良心血管和脑血管事件(MACCE)发生率为5.2%,无靶病变血运重建。在6个月随访时,MACCE发生率为10.4%,靶病变血管重建(TLR)率为1%。

结论

我们的中期数据显示,在所有患有严重钙化冠状动脉病变的患者队列中,轨道旋磨术作为一种斑块修饰工具具有良好的安全性和有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aea4/10532293/ea1db44b337c/jcm-12-05842-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aea4/10532293/fc689452ece2/jcm-12-05842-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aea4/10532293/ea1db44b337c/jcm-12-05842-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aea4/10532293/fc689452ece2/jcm-12-05842-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aea4/10532293/ea1db44b337c/jcm-12-05842-g002.jpg

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本文引用的文献

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J Clin Med. 2023 Jul 23;12(14):4844. doi: 10.3390/jcm12144844.
2
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Kardiol Pol. 2023;81(9):878-885. doi: 10.33963/KP.a2023.0152. Epub 2023 Jul 14.
3
Comparison of Orbital Atherectomy and Rotational Atherectomy in Calcified Left Main Disease: Short-Term Outcomes.
钙化性左主干病变中轨道旋磨术与旋切术的比较:短期结果
J Clin Med. 2023 Jun 13;12(12):4025. doi: 10.3390/jcm12124025.
4
First experience with orbital atherectomy in calcified unprotected left main percutaneous coronary intervention.钙化无保护左主干经皮冠状动脉介入治疗中旋磨术的首次经验
Postepy Kardiol Interwencyjnej. 2023 Mar;19(1):64-66. doi: 10.5114/aic.2022.121990. Epub 2022 Dec 22.
5
Fifteen-Year Nationwide Trend in Antiplatelet Treatment among Drug-Eluting Stent Recipients in Korea: Many Patients Receive Very Prolonged Dual-Antiplatelet Treatment, and Newer Drugs Are Replacing the Older Ones.韩国药物洗脱支架植入患者抗血小板治疗的十五年全国趋势:许多患者接受非常长时间的双联抗血小板治疗,且新药正在取代旧药。
J Clin Med. 2023 Apr 3;12(7):2675. doi: 10.3390/jcm12072675.
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Contemporary percutaneous management of coronary calcification: current status and future directions.当代经皮冠状动脉钙化的处理:现状与未来方向。
Open Heart. 2023 Feb;10(1). doi: 10.1136/openhrt-2022-002182.
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