Angsubhakorn Natthapon, Kang Nicolas, Fearon Colleen, Techorueangwiwat Chol, Swamy Pooja, Brilakis Emmanouil S, Bharadwaj Aditya S
Division of Cardiology, Loma Linda University Medical Center, Loma Linda, CA 92354, USA.
Department of Medicine, Loma Linda University Medical Center, Loma Linda, CA 92354, USA.
J Pers Med. 2022 Oct 3;12(10):1638. doi: 10.3390/jpm12101638.
Coronary artery calcification is increasingly prevalent in our patient population. It significantly limits the procedural success of percutaneous coronary intervention and is associated with a higher risk of adverse cardiovascular events both in the short-term and long-term. There are several modalities for modifying calcified plaque, such as balloon angioplasty (including specialty balloons), coronary atheroablative therapy (rotational, orbital, and laser atherectomy), and intravascular lithotripsy. We discuss each modality's relative advantages and disadvantages and the data supporting their use. This review also highlights the importance of intravascular imaging to characterize coronary calcification and presents an algorithm to tailor the calcium modification therapy based on specific coronary lesion characteristics.
冠状动脉钙化在我们的患者群体中越来越普遍。它显著限制了经皮冠状动脉介入治疗的手术成功率，并且与短期和长期不良心血管事件的较高风险相关。有几种用于改变钙化斑块的方法，如球囊血管成形术（包括特殊球囊）、冠状动脉粥样斑块消融治疗（旋转、轨道和激光斑块旋切术）以及血管内碎石术。我们讨论了每种方法的相对优缺点以及支持其使用的数据。本综述还强调了血管内成像对冠状动脉钙化进行特征描述的重要性，并提出了一种根据特定冠状动脉病变特征定制钙修饰治疗的算法。
