Kim Jong-Ho, Sohn Jong-Hee, Lee Jae-Jun, Kwon Young-Suk
Department of Anesthesiology and Pain Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon-si 24253, Republic of Korea.
Institute of New Frontier Research Team, Hallym University College of Medicine, Chuncheon-si 24252, Republic of Korea.
J Clin Med. 2023 Sep 12;12(18):5912. doi: 10.3390/jcm12185912.
Age-related differences in pain perception have been reported in various contexts; however, their impact on postoperative pain intensity remains poorly understood, especially across different surgical procedures. Data from five hospitals were retrospectively analyzed, encompassing patients who underwent 10 distinct surgical procedures. Numeric rating scale scores were used to assess the worst postoperative pain intensity during the 24 h after surgery. The multivariate linear regression model analyzed the relationship between age and pain intensity. Subgroup analyses were performed according to sex and patient-controlled analgesia (PCA). This study included 41,187 patients. Among the surgeries studied, lumbar spine fusion (β = -0.155, < 0.001) consistently and significantly exhibited a decrease in worst postoperative pain with increasing age. Similar trends were observed in cholecystectomy (β = -0.029, < 0.001) and several other surgeries; however, the results were inconsistent across all analyses. Surgeries with higher percentages of PCA administration had lower median worst-pain scores. In conclusion, age may affect postoperative pain intensity after specific surgeries; however, a comprehensive understanding of the complex interplay between age, surgical intervention, and pain intensity is required. Pain management strategies should consider various factors, including age-related variations.
在各种情况下均已报道了疼痛感知方面的年龄差异；然而，其对术后疼痛强度的影响仍知之甚少，尤其是在不同的外科手术中。对来自五家医院的数据进行了回顾性分析，涵盖接受了10种不同外科手术的患者。采用数字评分量表评分来评估术后24小时内最严重的术后疼痛强度。多变量线性回归模型分析了年龄与疼痛强度之间的关系。根据性别和患者自控镇痛（PCA）进行了亚组分析。本研究纳入了41187例患者。在所研究的手术中，腰椎融合术（β = -0.155，< 0.001）随着年龄的增长，术后最严重疼痛持续且显著降低。胆囊切除术（β = -0.029，< 0.001）及其他几种手术也观察到了类似趋势；然而，所有分析结果并不一致。PCA使用率较高的手术，其最严重疼痛评分中位数较低。总之，年龄可能会影响特定手术后的术后疼痛强度；然而，需要全面了解年龄、手术干预和疼痛强度之间复杂的相互作用。疼痛管理策略应考虑各种因素，包括与年龄相关的差异。
