Bae Seongryu, Jang Minwoo, Kim Gwon-Min, Yang Ja-Gyeong, Thapa Ngeemasara, Park Hye-Jin, Park Hyuntae
Department of Healthcare and Science, Dong-A University, Busan 49315, Republic of Korea.
Department of Convergence Medical Science, School of Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
J Clin Med. 2023 Sep 16;12(18):6009. doi: 10.3390/jcm12186009.
The purpose of this study is to examine how physical function, physical activity, and sleep are related to depressive symptoms in older adults using a nonlinear model. The participants were 283 Korean older adults aged 65 and older who met the study inclusion criteria. Depressive symptoms were measured using the shortened version of the Geriatric Depression Scale in Korean (SGDS-K). Physical activity and sleep time were objectively quantified by continuously monitoring participants over 20 consecutive days using a triaxial accelerometer. Physical function was evaluated using five distinct measurements: grip strength, gait speed, the Timed Up and Go Test (TUG), the Six-Minute Walk Test (SMWT), and the Five Times Sit to Stand Test (FTSST). The SMWT, gait speed, and MVPA exhibited a nonlinear relationship with depressive symptoms. However, other physical functions showed linear relationships. Also, sleep time showed a U-shaped trend starting at approximately 390 min. After adjusting for age, sex, drinking, and smoking in the logistic regression model, SMWT, MVPA, and sleep time were significantly associated with depressive symptoms. The outcomes highlight the importance of considering multiple factors in understanding depression among the elderly, particularly the intricate interactions between these elements and biological rhythms.
本研究的目的是使用非线性模型研究身体功能、身体活动和睡眠与老年人抑郁症状之间的关系。参与者为283名65岁及以上符合研究纳入标准的韩国老年人。使用韩国版老年抑郁量表简版（SGDS-K）测量抑郁症状。通过使用三轴加速度计连续20天对参与者进行持续监测，客观量化身体活动和睡眠时间。使用五项不同的测量方法评估身体功能：握力、步速、定时起立行走测试（TUG）、六分钟步行测试（SMWT）和五次坐立测试（FTSST）。SMWT、步速和中等至剧烈身体活动（MVPA）与抑郁症状呈非线性关系。然而，其他身体功能呈线性关系。此外，睡眠时间从约390分钟开始呈现U形趋势。在逻辑回归模型中调整年龄、性别、饮酒和吸烟因素后，SMWT、MVPA和睡眠时间与抑郁症状显著相关。研究结果突出了在理解老年人抑郁症时考虑多个因素的重要性，特别是这些因素与生物节律之间的复杂相互作用。
