• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[Etryptamine, a new designer drug with a fatal effect].

作者信息

Daldrup T, Heller C, Matthiesen U, Honus S, Bresges A, Haarhoff K

出版信息

Z Rechtsmed. 1986;97(1):61-8. doi: 10.1007/BF00200960.

DOI:10.1007/BF00200960
PMID:3776356
Abstract

Capsules with etryptamine have been commonly available on the market since the middle of 1985. Up to 1962 this CNS-stimulating, monoamine-oxidase-inhibiting drug was sold as an antidepressant (Monase). A case of fatal intoxication is reported. The exact amount of etryptamine taken several hours before death are not known, but it could have been in the range of 700 mg. This drug was detected in tissue by means of common analytical techniques (GLC, GC-MS, HPLC, TLC). Etryptamine cross-reacts with the Emit-st amphetamine assay and can also be detected in urine using these techniques. The level in postmortem blood was 1.1 mg/l. The effects the young man showed were like those known from intoxication with amphetamines, MAO inhibitors, and thymoleptics. Malignant hyperthermia is discussed as a possible cause of death. It is suggested that trade in etryptamine should be controlled.

摘要

相似文献

1
[Etryptamine, a new designer drug with a fatal effect].
Z Rechtsmed. 1986;97(1):61-8. doi: 10.1007/BF00200960.
2
Fatal intoxication involving etryptamine.涉及乙胺的致命中毒。
J Forensic Sci. 1993 May;38(3):721-5.
3
Fatality due to acute alpha-methyltryptamine intoxication.急性α-甲基色胺中毒致死
J Anal Toxicol. 2005 Jul-Aug;29(5):394-7. doi: 10.1093/jat/29.5.394.
4
Studies on the toxicology of alpha-methyl- and alpha-ethyltryptamine acetates (Monase). II. Chronic studies.α-甲基和α-乙基色胺乙酸酯(莫纳赛)的毒理学研究。II. 慢性研究。
Toxicol Appl Pharmacol. 1962 Nov;4:697-709. doi: 10.1016/0041-008x(62)90099-6.
5
[Antireserpinic activity of 2 new psychoenergizing drugs: tranylcypromine (SKF 385) and etryptamine (Monase)].[两种新型精神振奋药物的抗利血平活性:反苯环丙胺(SKF 385)和依色胺(莫纳明)]
Riv Sper Freniatr Med Leg Alien Ment. 1961 Dec 31;85:1331-52.
6
Etryptamine acetate--a new antidepressant chemical.醋酸麦角乙胺——一种新型抗抑郁化学物质。
J Neuropsychiatr. 1962 Jan-Feb;3:181-5.
7
In vitro monoamine oxidase inhibition potential of alpha-methyltryptamine analog new psychoactive substances for assessing possible toxic risks.用于评估潜在毒性风险的α-甲基色胺类似物新型精神活性物质的体外单胺氧化酶抑制潜力
Toxicol Lett. 2017 Apr 15;272:84-93. doi: 10.1016/j.toxlet.2017.03.007. Epub 2017 Mar 14.
8
Tissue distribution of amphetamine isomers in a fatal overdose.苯丙胺异构体在致命性过量中毒中的组织分布。
J Anal Toxicol. 1997 May-Jun;21(3):236-9. doi: 10.1093/jat/21.3.236.
9
LC-MS/MS screening method for designer amphetamines, tryptamines, and piperazines in serum.基于 LC-MS/MS 的血清中设计类苯丙胺、色胺和哌嗪类物质的筛查方法。
Anal Bioanal Chem. 2010 Apr;396(7):2403-14. doi: 10.1007/s00216-009-3394-4. Epub 2010 Jan 13.
10
Memory function of patients taking etryptamine acetate.服用醋酸色胺的患者的记忆功能。
J Nerv Ment Dis. 1961 Sep;133:213-5. doi: 10.1097/00005053-196109000-00004.

引用本文的文献

1
α-Ethyltryptamine: A Ratiocinatory Review of a Forgotten Antidepressant.α-乙基色胺:对一种被遗忘的抗抑郁药的推理综述。
ACS Pharmacol Transl Sci. 2023 Nov 7;6(12):1780-1789. doi: 10.1021/acsptsci.3c00139. eCollection 2023 Dec 8.
2
Toxicology and Analysis of Psychoactive Tryptamines.精神作用色胺类的毒理学和分析。
Int J Mol Sci. 2020 Dec 4;21(23):9279. doi: 10.3390/ijms21239279.
3
Recreational use, analysis and toxicity of tryptamines.色胺类物质的消遣性使用、分析及毒性

本文引用的文献

1
Human tolerance of alpha-ethyltryptamine.人类对α-乙基色胺的耐受性。
J Neuropsychiatr. 1961 Feb;2(Suppl 1):77-9.
2
Effects in normal man of alpha-methyltryptamine and alpha-ethyltryptamine.α-甲基色胺和α-乙基色胺对正常人的影响。
Clin Pharmacol Ther. 1961 Nov-Dec;2:722-6. doi: 10.1002/cpt196126722.
3
DIGITAL COMPUTER ANALYSIS OF HUMAN ISOTOPIC DRUG KINETICS.人体同位素药物动力学的数字计算机分析
Curr Neuropharmacol. 2015 Jan;13(1):26-46. doi: 10.2174/1570159X13666141210222409.
4
alpha-Ethyltryptamine (alpha-ET) as a discriminative stimulus in rats.α-乙基色胺(α-ET)作为大鼠的辨别性刺激物。
Pharmacol Biochem Behav. 2006 Oct;85(2):448-53. doi: 10.1016/j.pbb.2006.09.014. Epub 2006 Nov 16.
5
Behavioral characterization of alpha-ethyltryptamine, a tryptamine derivative with MDMA-like properties in rats.α-乙基色胺的行为特征研究,一种在大鼠中具有类似摇头丸特性的色胺衍生物。
Psychopharmacology (Berl). 1993;113(2):284-7. doi: 10.1007/BF02245712.
Int J Appl Radiat Isot. 1964 May;15:263-8. doi: 10.1016/0020-708x(64)90147-4.
4
[PHARMACOLOGICAL CHARACTERIZATION AND DETECTION OF HALLUCINOGENIC SUBSTANCES. I. HYPERTHERMIC ACTION IN THE RABBIT].[致幻物质的药理学特性与检测。I. 对家兔的体温升高作用]
Arch Int Pharmacodyn Ther. 1963 Oct 1;145:528-45.
5
[The anticataleptic activity of some antidepressives (thymoleptics)].[某些抗抑郁药(抗抑郁剂)的抗惊厥活性]
Arzneimittelforschung. 1963 Feb;13:103-9.
6
A comparison of various amine oxidase inhibitors as antidepressants.各类胺氧化酶抑制剂作为抗抑郁药的比较。
Psychosomatics. 1962 Jan-Feb;3:53-6. doi: 10.1016/s0033-3182(62)72752-0.
7
Clinical studies with ethyltryptamine.关于乙色胺的临床研究。
J Neuropsychiatr. 1961 Feb;2(Suppl 1):73-6.
8
A monoamine oxidase inhibitor in the treatment of organic disease.一种用于治疗器质性疾病的单胺氧化酶抑制剂。
J Neuropsychiatr. 1961 Feb;2(Suppl 1):80-5.
9
Clinical experiences with etryptamine in office practice.依色胺在门诊实践中的临床经验。
J Neuropsychiatr. 1961 Feb;2(Suppl 1):58-60.
10
Treatment of geriatric patients with etryptamine acetate.用醋酸麦角乙胺治疗老年患者。
J Neuropsychiatr. 1961 Feb;2(Suppl1):64-5.