Jakobsen J, Christensen K S, Støckel M
Z Rheumatol. 1986 Jul-Aug;45(4):152-4.
The disappearance rate of 131I-albumin from the knee joint in six rabbits was measured before and after intraarticular injection of 7.5 mg triamcinolonhexacetonide (Lederspan). A significant decrease in the synovial permeability was demonstrated after injection of triamcinolonhexacetonide (average 64 percent). It is concluded that this demonstrates that corticosteroids have a direct effect on the synovial membrane, which may be an important mechanism whereby they exert their therapeutic effect upon joints.
在六只兔子的膝关节内注射7.5毫克曲安奈德（利美达松）前后，测量了131I-白蛋白从膝关节的消失率。注射曲安奈德后，滑膜通透性显著降低（平均64%）。由此得出结论，这表明皮质类固醇对滑膜有直接作用，这可能是它们对关节发挥治疗作用的一个重要机制。
