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[阿尔茨海默病中的情感障碍]

[Affective disorders in Alzheimer's disease].

作者信息

Sokol'chik E I

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1986;86(9):1376-80.

PMID:3776424
Abstract

Thirty-two patients with Alzheimer's disease and affective disturbances were studied. Depressive manifestations were found to be most frequent. In some cases depressive states developed in response to specific psychotraumatizing situations. In the majority of cases the depressions were spontaneous. Sometimes, they were pronounced and ran at the so-called endogenic level even at the stage of full-blown manifestations of the mentally-deteriorating process in the brain. The mere presence of dementia did not prevent the development of marked depressive symptomatology with suicidal tendencies. Deepening of deficient manifestations led to certain changes and simplification of depressive disturbances as well as to their instability. No correlation was revealed between the depth of the senile atrophic process, its rate and severity of affective symptomatology.

摘要

对32例患有阿尔茨海默病和情感障碍的患者进行了研究。发现抑郁表现最为常见。在某些情况下,抑郁状态是对特定精神创伤性情境的反应。在大多数情况下,抑郁是自发产生的。有时,即使在大脑精神衰退过程全面显现的阶段,抑郁也很明显且达到所谓的内源性水平。痴呆的存在本身并不妨碍伴有自杀倾向的明显抑郁症状学的发展。缺陷表现的加重导致抑郁障碍出现某些变化和简化,以及其不稳定性。未发现老年萎缩过程的深度、其进展速度与情感症状学的严重程度之间存在相关性。

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