Department of Endocrinology and Nutrition, Consorci Sanitari Alt Penedès-Garraf, Espirall, 61, 08720 Vilafranca del Penedès, Spain.
Department of Endocrinology and Nutrition, Hospital del Mar, Passeig Marítim, 25-29, 08003 Barcelona, Spain.
Nutrients. 2023 Sep 16;15(18):4012. doi: 10.3390/nu15184012.
(1) Background: The objectives of this study were to evaluate the concurrent and predictive validity and the applicability of the global leadership initiative on malnutrition (GLIM) criteria in patients hospitalized for acute medical conditions. (2) Methods: prospective cohort study with patients hospitalized for acute medical conditions. For validation, the methodology proposed by the GLIM group of experts was used. Sensitivity and specificity values greater than 80% with respect to those for the subjective global assessment (SGA) were necessary for concurrent validation. The time necessary to complete each nutritional assessment test was determined. (3) Results: A total of 119 patients were evaluated. The SGA was applied to the entire cohort, but the GLIM criteria could not be applied to 3.4% of the patients. The sensitivity and specificity of the GLIM criteria with respect to those for the SGA to detect malnutrition were 78.0 and 86.2%, respectively. The GLIM predictive validity criterion was fulfilled because patients with malnutrition more frequently had a hospital stay >10 days (odds ratio of 2.98 (1.21-7.60)). The GLIM criteria required significantly more time for completion than did the SGA ( = 0.006). (4) Conclusion: The results of this study do not support the use of the GLIM criteria over the SGA for the diagnosis of malnutrition in patients hospitalized for acute medical conditions.
(1) 背景:本研究旨在评估全球营养不良领导倡议 (GLIM) 标准在急性医疗条件住院患者中的同时性和预测性有效性以及适用性。(2) 方法:前瞻性队列研究,纳入急性医疗条件住院患者。为了进行验证,采用 GLIM 专家组提出的方法。与主观整体评估 (SGA) 相比,针对同时性验证,需要大于 80%的敏感性和特异性值。确定完成每项营养评估测试所需的时间。(3) 结果:共评估了 119 例患者。对整个队列进行了 SGA 评估,但 3.4%的患者无法应用 GLIM 标准。GLIM 标准对 SGA 检测营养不良的敏感性和特异性分别为 78.0%和 86.2%。GLIM 预测有效性标准得到满足,因为营养不良患者的住院时间更长 (>10 天)(比值比为 2.98(1.21-7.60))。GLIM 标准完成所需的时间明显长于 SGA(=0.006)。(4) 结论:本研究结果不支持在急性医疗条件住院患者中使用 GLIM 标准替代 SGA 来诊断营养不良。