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肝癌患者围手术期营养诊断与支持策略的进展

Advancements in nutritional diagnosis and support strategies during the perioperative period for patients with liver cancer.

作者信息

Li Xiao-Qin, Liang Yun, Huang Chen-Feng, Li Sui-Ning, Cheng Lei, You Chuan, Liu Yao-Xia, Wang Tao

机构信息

Department of Hepatobiliary Surgery, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China.

Department of Paediatric Surgery, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China.

出版信息

World J Gastrointest Surg. 2024 Aug 27;16(8):2409-2425. doi: 10.4240/wjgs.v16.i8.2409.

Abstract

Liver cancer represents a grave hepatic condition and constitutes a significant global health concern. Surgical resection remains the principal therapeutic modality for liver cancer. Nevertheless, perioperative malnutrition exerts a notable impact on patients with liver cancer, emerging as an independent risk factor for disease mortality and adverse outcomes. Hence, precise nutritional diagnosis and timely nutritional support hold the potential to enhance therapeutic efficacy and quality of life for liver cancer patients. This study represents a meticulous foray into the literature, extracting data from PubMed, Web of Science, and EMBASE databases, with a focus on the past 5 years. It scrutinizes the impact of malnutrition on patients undergoing liver cancer surgery, the etiological underpinnings of malnutrition within this patient cohort, the critical assessment of perioperative nutritional status, and the strategic approaches to nutritional support. Utilizing rigorous inclusion and exclusion criteria, the amassed scholarly works are meticulously synthesized, methodically organized, and categorically elaborated upon. Ultimately, the authors propose the incorporation of a multidisciplinary nutrition management team during the perioperative period, comprising nutritionists, pharmacists, physicians, nurses, psychologists, and rehabilitation therapists, among other specialized professionals. Together, they collaborate to devise and implement personalized nutritional support plans, monitor patients' nutritional status, and make necessary adjustments as required. Through comprehensive management and intervention, improvements in the nutritional status of liver cancer patients can be achieved, thereby enhancing surgical success rates and facilitating postoperative recovery. It is believed that this manuscript will offer valuable insights to advance the nutritional management during the perioperative phase of liver cancer, aiding in ameliorating patients' nutritional status and treatment outcomes.

摘要

肝癌是一种严重的肝脏疾病,是全球重大的健康问题。手术切除仍然是肝癌的主要治疗方式。然而,围手术期营养不良对肝癌患者有显著影响,成为疾病死亡率和不良结局的独立危险因素。因此,精确的营养诊断和及时的营养支持有可能提高肝癌患者的治疗效果和生活质量。本研究对文献进行了细致的探究,从PubMed、科学网和EMBASE数据库中提取数据,重点关注过去5年的情况。它审视了营养不良对接受肝癌手术患者的影响、该患者群体中营养不良的病因基础、围手术期营养状况的关键评估以及营养支持的策略方法。利用严格的纳入和排除标准,对收集到的学术著作进行精心综合、系统整理和分类阐述。最终,作者建议在围手术期组建一个多学科营养管理团队,成员包括营养师、药剂师、医生、护士、心理学家和康复治疗师等专业人员。他们共同合作制定和实施个性化的营养支持计划,监测患者的营养状况,并根据需要进行必要的调整。通过全面管理和干预,可以改善肝癌患者的营养状况,从而提高手术成功率并促进术后恢复。相信本手稿将为推进肝癌围手术期营养管理提供有价值的见解,有助于改善患者的营养状况和治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a01/11362955/335b6bebb49d/WJGS-16-2409-g001.jpg

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