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伴动脉夹层动脉瘤和脑出血的多发性肌炎

Polymyositis associated with dissecting aneurysm of arteries and intracerebral hemorrhage.

作者信息

Hatanaka K, Yutani C, Fujieda T, Yamaguchi T

出版信息

Acta Pathol Jpn. 1986 Aug;36(8):1217-23. doi: 10.1111/j.1440-1827.1986.tb02842.x.

Abstract

Dissecting aneurysm and stroke are a rare complication of polymyositis. The present report describes an autopsy case of a 53-year-old woman, who suffered from polymyositis accompanied by dissecting aneurysms of right external iliac and right renal arteries, and furthermore, intracerebral hemorrhage. The latter was caused by necrotizing angiitis. The patient had no abnormal anatomical changes such as coarctation of aorta, aortic stenosis, bicuspid aortic valve or Marfan's syndrome. Atherosclerosis in the patient was mild, and cystic medial necrosis of aorta and arteries was not found. Since the patient was attacked by dissections of arteries following long-term steroid therapy, a possibility can be raised that arterial dissection was attributable to steroid treatment besides necrotizing angiitis complicating in polymyositis.

摘要

夹层动脉瘤和中风是多发性肌炎的罕见并发症。本报告描述了一例53岁女性的尸检病例,该患者患有多发性肌炎,伴有右髂外动脉和右肾动脉夹层动脉瘤,此外还发生了脑出血。后者由坏死性血管炎引起。患者没有诸如主动脉缩窄、主动脉狭窄、二叶主动脉瓣或马凡综合征等异常解剖学改变。患者的动脉粥样硬化较轻,未发现主动脉和动脉的囊性中层坏死。由于患者在长期类固醇治疗后发生动脉夹层,除了多发性肌炎并发坏死性血管炎外,还可能是类固醇治疗导致了动脉夹层。

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