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用于呼吸衰竭的“延长式”静脉-动脉体外膜肺氧合支持:一名婴儿的治疗结果

"Prolonged" venoarterial extracorporeal membrane oxygenation support for respiratory failure: Outcome in an infant.

作者信息

Shah Shreya Bharat, Joshi Reena Khantwal, Rattan Avvayyam, Aggarwal Neeraj, Joshi Raja

机构信息

Department of Anaesthesiology, Pain Medicine and Critical Care Medicine, All India Institute of Medical Sciences, New Delhi, India.

Department of Paediatric Cardiac Sciences, Sir Ganga Ram Hospital, New Delhi, India.

出版信息

Ann Pediatr Cardiol. 2023 Mar-Apr;16(2):134-137. doi: 10.4103/apc.apc_45_22. Epub 2023 Aug 16.

DOI:10.4103/apc.apc_45_22
PMID:37767161
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10522154/
Abstract

Extracorporeal membrane oxygenation (ECMO) is a form of extracorporeal life support which provides cardiorespiratory support to patients with potentially reversible pathophysiological processes. ECMO has evolved over the past few decades as a standard technology for neonatal severe respiratory support. However, its use in the pediatric population has increased only since 2009. We report a case of a 9-month infant who required a prolonged (789 h) venoarterial ECMO for severe acute respiratory distress consequent to pneumonia probably secondary to aspiration. He was discharged after this prolonged ECMO run without any obvious unfavorable outcome and is neurodevelopmentally sound at a 26-month follow-up.

摘要

体外膜肺氧合(ECMO)是一种体外生命支持形式,为具有潜在可逆病理生理过程的患者提供心肺支持。在过去几十年中,ECMO已发展成为新生儿严重呼吸支持的标准技术。然而,其在儿科人群中的应用直到2009年才开始增加。我们报告一例9个月大的婴儿,因可能继发于误吸的肺炎导致严重急性呼吸窘迫,需要长时间(789小时)的静脉-动脉ECMO支持。在这次长时间的ECMO支持后,他顺利出院,没有任何明显的不良后果,在26个月的随访中神经发育正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48dc/10522154/519cc5188a31/APC-16-134-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48dc/10522154/1cf5f1e48f2d/APC-16-134-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48dc/10522154/519cc5188a31/APC-16-134-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48dc/10522154/1cf5f1e48f2d/APC-16-134-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48dc/10522154/519cc5188a31/APC-16-134-g002.jpg

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本文引用的文献

1
Extracorporeal Membrane Oxygenation for Severe Pediatric Respiratory Failure.体外膜肺氧合治疗小儿严重呼吸衰竭
Respir Care. 2017 Jun;62(6):732-750. doi: 10.4187/respcare.05338.
2
Determining comorbidities and quality of life among pediatric survivors of extracorporeal life support.确定体外生命支持儿科幸存者的合并症和生活质量。
J Crit Care. 2015 Oct;30(5):1085-9. doi: 10.1016/j.jcrc.2015.06.017. Epub 2015 Jun 24.
3
20-year experience of prolonged extracorporeal membrane oxygenation in critically ill children with cardiac or pulmonary failure.
20 年危重病儿童心肺衰竭体外膜肺氧合延长治疗经验。
Ann Thorac Surg. 2012 May;93(5):1584-90. doi: 10.1016/j.athoracsur.2012.01.008. Epub 2012 Mar 14.
4
Extracorporeal membrane oxygenation for pediatric respiratory failure: Survival and predictors of mortality.体外膜肺氧合治疗小儿呼吸衰竭:生存率和死亡率预测因素。
Crit Care Med. 2011 Feb;39(2):364-70. doi: 10.1097/CCM.0b013e3181fb7b35.
5
Two years' follow-up of newborn infants after extracorporeal membrane oxygenation (ECMO).体外膜肺氧合(ECMO)治疗后新生儿的两年随访
Eur J Cardiothorac Surg. 2000 Sep;18(3):328-33. doi: 10.1016/s1010-7940(00)00514-5.