Department of Emergency Medicine, Faculty of Medicine, Dokuz Eylul University, Balcova, 35340, Izmir, Turkey.
ESC Heart Fail. 2023 Dec;10(6):3604-3611. doi: 10.1002/ehf2.14537. Epub 2023 Sep 29.
The National Early Warning Score (NEWS) is a scoring system that predicts increased mortality and morbidity in critical diseases. The National Early Warning Score + Lactate (NEWS + L) score was created by adding lactate values to this scoring system. In our study, we aimed to determine the value of the NEWS + L score in predicting clinical deterioration in patients presenting with acute decompensated heart failure (chronic heart failure).
In this observational, cross-sectional study, patients with decompensated heart failure who were admitted to the emergency department between 1 October 2020 and 31 December 2020 were included. Patients were divided into two groups: those with and without poor prognostic outcomes. The main outcomes were in-hospital mortality, discharge after treatment in the emergency department, admission to the ward, and admission to the intensive care unit. We analysed a total of 141 applications from 130 patients. The mean age was 72.6 ± 11.8 years, and 50.8% were female. Poor prognostic outcomes were observed in 92 (65%) patients. There was no difference between the patients with and without poor prognostic outcomes in terms of mean age, gender, and comorbidities, except for atrial fibrillation. There was a statistically significant difference between the patients without and with poor prognosis outcomes in terms of NEWS {3 [interquartile range (IQR): 0-5] and 6 [IQR: 3-8]} and NEWS + L scores [4.7 (IQR: 2.3-7.2) and 8.0 (IQR: 5.2-10.4)] (P < 0.001). The area under the curve values for predicting poor prognosis were calculated as 0.719 for NEWS, 0.734 for NEWS + L, and 0.601 for lactate values. The rate of poor prognostic outcomes was higher (79%) in patients with moderate and high NEWS scores. Patients with Q1 NEWS + L scores had a lower rate of poor prognostic outcomes, while patients with Q2, Q3, and Q4 scores of NEWS + L had a higher rate of poor prognostic outcomes.
The NEWS score and the addition of the lactate value to this score, the NEWS + L score, were higher in patients with poor prognostic outcomes who presented with decompensated heart failure in our emergency department. NEWS + L slightly outperformed the NEWS score in predicting prognosis. The NEWS + L score shows promise as a prognostic indicator for patients with decompensated heart failure presenting to the emergency department.
国家早期预警评分(NEWS)是一种预测危急疾病患者死亡率和发病率增加的评分系统。NEWS+乳酸评分通过在该评分系统中添加乳酸值而创建。在我们的研究中,我们旨在确定 NEWS+乳酸评分在预测因急性失代偿性心力衰竭(慢性心力衰竭)就诊的患者临床恶化方面的价值。
在这项观察性、横断面研究中,纳入了 2020 年 10 月 1 日至 2020 年 12 月 31 日期间在急诊科就诊的失代偿性心力衰竭患者。将患者分为预后不良组和无预后不良组。主要结局是院内死亡率、急诊科治疗后出院、入住病房和入住重症监护病房。我们共分析了 130 例患者的 141 例应用。平均年龄为 72.6±11.8 岁,50.8%为女性。92 例(65%)患者预后不良。在平均年龄、性别和合并症方面,预后不良和无预后不良的患者之间没有差异,但房颤除外。在 NEWS[3(四分位距(IQR):0-5]和 6[IQR:3-8])和 NEWS+乳酸评分[4.7(IQR:2.3-7.2)和 8.0(IQR:5.2-10.4)]方面,预后不良和无预后不良的患者之间存在统计学显著差异(P<0.001)。预测预后不良的曲线下面积值分别为 NEWS 为 0.719、NEWS+乳酸为 0.734、乳酸值为 0.601。中高危 NEWS 评分患者的预后不良发生率较高(79%)。Q1 NEWS+乳酸评分患者的预后不良发生率较低,而 Q2、Q3 和 Q4 NEWS+乳酸评分患者的预后不良发生率较高。
在我们的急诊科,因失代偿性心力衰竭就诊的预后不良患者的 NEWS 评分和乳酸值加入该评分后的 NEWS+乳酸评分更高。NEWS+乳酸评分在预测预后方面略优于 NEWS 评分。NEWS+乳酸评分有望成为因失代偿性心力衰竭就诊的患者的预后指标。