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急诊失代偿性心力衰竭患者 NEWS+Lactate 评分的预后价值。

Prognostic value of the NEWS + Lactate score in patients with decompensated heart failure in the emergency department.

机构信息

Department of Emergency Medicine, Faculty of Medicine, Dokuz Eylul University, Balcova, 35340, Izmir, Turkey.

出版信息

ESC Heart Fail. 2023 Dec;10(6):3604-3611. doi: 10.1002/ehf2.14537. Epub 2023 Sep 29.

Abstract

AIMS

The National Early Warning Score (NEWS) is a scoring system that predicts increased mortality and morbidity in critical diseases. The National Early Warning Score + Lactate (NEWS + L) score was created by adding lactate values to this scoring system. In our study, we aimed to determine the value of the NEWS + L score in predicting clinical deterioration in patients presenting with acute decompensated heart failure (chronic heart failure).

METHODS AND RESULTS

In this observational, cross-sectional study, patients with decompensated heart failure who were admitted to the emergency department between 1 October 2020 and 31 December 2020 were included. Patients were divided into two groups: those with and without poor prognostic outcomes. The main outcomes were in-hospital mortality, discharge after treatment in the emergency department, admission to the ward, and admission to the intensive care unit. We analysed a total of 141 applications from 130 patients. The mean age was 72.6 ± 11.8 years, and 50.8% were female. Poor prognostic outcomes were observed in 92 (65%) patients. There was no difference between the patients with and without poor prognostic outcomes in terms of mean age, gender, and comorbidities, except for atrial fibrillation. There was a statistically significant difference between the patients without and with poor prognosis outcomes in terms of NEWS {3 [interquartile range (IQR): 0-5] and 6 [IQR: 3-8]} and NEWS + L scores [4.7 (IQR: 2.3-7.2) and 8.0 (IQR: 5.2-10.4)] (P < 0.001). The area under the curve values for predicting poor prognosis were calculated as 0.719 for NEWS, 0.734 for NEWS + L, and 0.601 for lactate values. The rate of poor prognostic outcomes was higher (79%) in patients with moderate and high NEWS scores. Patients with Q1 NEWS + L scores had a lower rate of poor prognostic outcomes, while patients with Q2, Q3, and Q4 scores of NEWS + L had a higher rate of poor prognostic outcomes.

CONCLUSIONS

The NEWS score and the addition of the lactate value to this score, the NEWS + L score, were higher in patients with poor prognostic outcomes who presented with decompensated heart failure in our emergency department. NEWS + L slightly outperformed the NEWS score in predicting prognosis. The NEWS + L score shows promise as a prognostic indicator for patients with decompensated heart failure presenting to the emergency department.

摘要

目的

国家早期预警评分(NEWS)是一种预测危急疾病患者死亡率和发病率增加的评分系统。NEWS+乳酸评分通过在该评分系统中添加乳酸值而创建。在我们的研究中,我们旨在确定 NEWS+乳酸评分在预测因急性失代偿性心力衰竭(慢性心力衰竭)就诊的患者临床恶化方面的价值。

方法和结果

在这项观察性、横断面研究中,纳入了 2020 年 10 月 1 日至 2020 年 12 月 31 日期间在急诊科就诊的失代偿性心力衰竭患者。将患者分为预后不良组和无预后不良组。主要结局是院内死亡率、急诊科治疗后出院、入住病房和入住重症监护病房。我们共分析了 130 例患者的 141 例应用。平均年龄为 72.6±11.8 岁,50.8%为女性。92 例(65%)患者预后不良。在平均年龄、性别和合并症方面,预后不良和无预后不良的患者之间没有差异,但房颤除外。在 NEWS[3(四分位距(IQR):0-5]和 6[IQR:3-8])和 NEWS+乳酸评分[4.7(IQR:2.3-7.2)和 8.0(IQR:5.2-10.4)]方面,预后不良和无预后不良的患者之间存在统计学显著差异(P<0.001)。预测预后不良的曲线下面积值分别为 NEWS 为 0.719、NEWS+乳酸为 0.734、乳酸值为 0.601。中高危 NEWS 评分患者的预后不良发生率较高(79%)。Q1 NEWS+乳酸评分患者的预后不良发生率较低,而 Q2、Q3 和 Q4 NEWS+乳酸评分患者的预后不良发生率较高。

结论

在我们的急诊科,因失代偿性心力衰竭就诊的预后不良患者的 NEWS 评分和乳酸值加入该评分后的 NEWS+乳酸评分更高。NEWS+乳酸评分在预测预后方面略优于 NEWS 评分。NEWS+乳酸评分有望成为因失代偿性心力衰竭就诊的患者的预后指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/545b/10682865/b5245c870a1f/EHF2-10-3604-g001.jpg

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