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Register-based randomized trials: the new power-tool in orthopedic research?基于注册的随机试验：骨科研究中的新有力工具？
Acta Orthop. 2023 Sep 29;94:490-492. doi: 10.2340/17453674.2023.19661.
2
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本文引用的文献

1
Effect of single versus multiple prophylactic antibiotic doses on prosthetic joint infections following primary total hip arthroplasty in patients with osteoarthritis at public and private hospitals in Denmark: protocol for a nationwide cross-over, cluster randomised, non-inferiority trial [The Pro-Hip-Quality Trial].丹麦公立和私立医院骨性关节炎患者初次全髋关节置换术后使用单剂量与多剂量预防性抗生素对人工关节感染的影响：一项全国交叉、集群随机、非劣效性试验方案[Pro-Hip-Quality 试验]。
BMJ Open. 2023 Aug 21;13(8):e071487. doi: 10.1136/bmjopen-2022-071487.
2
The use of antibiotic-loaded bone cement and systemic antibiotic prophylactic use in 2,971,357 primary total knee arthroplasties from 2010 to 2020: an international register-based observational study among countries in Africa, Europe, North America, and Oceania.在 2010 年至 2020 年间，对来自非洲、欧洲、北美洲和大洋洲的 2971357 例初次全膝关节置换术进行了一项基于国际注册的观察性研究，以评估抗生素骨水泥的使用和全身预防性使用抗生素的情况。
Acta Orthop. 2023 Aug 9;94:416-425. doi: 10.2340/17453674.2023.17737.
3
High-dose dual-antibiotic loaded cement for hip hemiarthroplasty in the UK (WHiTE 8): a randomised controlled trial.英国髋关节半髋关节置换术中高剂量双联抗生素加载骨水泥（WHiTE 8）：一项随机对照试验。
Lancet. 2023 Jul 15;402(10397):196-202. doi: 10.1016/S0140-6736(23)00962-5. Epub 2023 Jun 21.
4
Study protocol: The DAICY trial-dual versus single-antibiotic impregnated cement in primary hemiarthroplasty for femoral neck fracture-a register-based cluster-randomized crossover-controlled trial.研究方案：DAICY 试验-双 versus 单抗生素浸渍骨水泥在股骨颈骨折初次半髋关节置换术中的应用-基于注册的聚类随机交叉对照试验。
Acta Orthop. 2022 Oct 5;93:794-800. doi: 10.2340/17453674.2022.4819.
5
Effect of Aspirin vs Enoxaparin on Symptomatic Venous Thromboembolism in Patients Undergoing Hip or Knee Arthroplasty: The CRISTAL Randomized Trial.髋关节或膝关节置换术后阿司匹林与依诺肝素对有症状静脉血栓栓塞症的影响：CRISTAL 随机试验。
JAMA. 2022 Aug 23;328(8):719-727. doi: 10.1001/jama.2022.13416.
6
Robotic-assisted surgery and kinematic alignment in total knee arthroplasty (RASKAL study): a protocol of a national registry-nested, multicentre, 2×2 factorial randomised trial assessing clinical, intraoperative, functional, radiographic and survivorship outcomes.机器人辅助手术和全膝关节置换术中的运动学对线（RASKAL 研究）：一项全国登记处嵌套、多中心、2×2 析因随机试验的方案，评估临床、术中、功能、影像学和生存率结果。
BMJ Open. 2022 Jun 10;12(6):e051088. doi: 10.1136/bmjopen-2021-051088.
7
Study protocol: The SunBurst trial-a register-based, randomized controlled trial on thoracolumbar burst fractures.研究方案：SunBurst试验——一项基于登记的胸腰椎爆裂骨折随机对照试验。
Acta Orthop. 2022 Jan 24;93:256-263. doi: 10.2340/17453674.2022.1614.
8
The Swedish Fracture Register - ten years of experience and 600,000 fractures collected in a National Quality Register.瑞典骨折登记处 - 十年经验和 600,000 例骨折纳入国家质量登记处。
BMC Musculoskelet Disord. 2022 Feb 11;23(1):141. doi: 10.1186/s12891-022-05062-w.
9
Cemented or Uncemented Hemiarthroplasty for Intracapsular Hip Fracture.骨水泥型或非骨水泥型人工股骨头置换术治疗囊内型髋关节骨折。
N Engl J Med. 2022 Feb 10;386(6):521-530. doi: 10.1056/NEJMoa2108337.
10
Antibiotic-Loaded Bone Cement in Prevention of Periprosthetic Joint Infections in Primary Total Knee Arthroplasty: A Register-based Multicentre Randomised Controlled Non-inferiority Trial (ALBA trial).抗生素骨水泥在预防初次全膝关节置换术后假体周围感染中的应用：一项基于注册的多中心随机对照非劣效性试验（ALBA 试验）。
BMJ Open. 2021 Jan 28;11(1):e041096. doi: 10.1136/bmjopen-2020-041096.

Register-based randomized trials: the new power-tool in orthopedic research?

作者信息

Hailer Nils P, Furnes Ove, Mäkelä Keijo, Overgaard Søren

机构信息

Department of Surgical Sciences - Orthopaedics, Uppsala University, Uppsala, Sweden.

Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway; Department of Clinical Medicine, University of Bergen, Norway.

出版信息

Acta Orthop. 2023 Sep 29;94:490-492. doi: 10.2340/17453674.2023.19661.

DOI:10.2340/17453674.2023.19661
PMID:37772890
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10540786/
Abstract
摘要