多排螺旋 CT 和 Gd-EOB-DTPA 增强 MRI 在早期肝细胞肝癌患者诊断和治疗中的差异。
Differences in the Diagnosis and Treatment of Patients with Early-Stage Hepatocellular Liver Cancer by Multi-Row Spiral CTMDCT and Gd-EOB-DTPA-Enhanced MRI.
出版信息
Altern Ther Health Med. 2024 Jan;30(1):31-35.
OBJECTIVE
The assessment of liver cancer lesion characteristics mainly relies on multi-row spiral computed tomography (MDCT) and magnetic resonance imaging (MRI). MDCT suffers from a series of problems, such as low soft tissue contrast and large tumor boundary errors, which lead to its limited practical application value in liver cancer. In contrast, Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced MRI has better soft-tissue contrast than MDCT and increases the clarity of liver cancer lesions. To investigate the differences between MDCT and Gd-EOB-DTPA-enhanced MRI in managing patients with hepatocellular liver cancer.
METHODS
A total of 80 patients diagnosed with hepatocellular carcinoma of the liver, who received treatment at our hospital between September 2020 and September 2022, were included in this study. These patients were evenly divided into two groups: the observation group and the control group, with 40 cases in each. The aim of this study was to compare the differences in signal indices of hepatobiliary stage between the two groups in patients with hepatocellular carcinoma.
RESULTS
A total of 89 cancer nodules were detected in patients by MDCT, and 109 cancer nodules were detected in patients by Gd-EOB-DTPA-enhanced MRI. When the number of nodules detected by both imaging modalities was statistically analyzed, the differences in the number of hepatocellular carcinoma (HCC) nodules detected by MDCT and Gd-EOB-DTPA-enhanced MRI were statistically significant (P < .05). Further analysis of the data by single cancer nodule, multiple cancer nodules, and cancer nodule size showed that the difference between the two imaging modalities was statistically significant (P < .05) in the diagnosis of patients with a single liver cancer nodule or multiple liver cancer nodules (94.8% vs.81.3%). The difference in the comparison was statistically significant (P < .05).
CONCLUSION
Gd-EOB-DTPA-enhanced MRI demonstrates superior diagnostic efficacy in detecting small hepatocellular carcinoma, offers improved staging capabilities for hepatocellular carcinoma, and provides more precise guidance for treatment planning.Consequently, Gd-EOB-DTPA-enhanced MRI exhibits exceptional diagnostic value and serves as a valuable tool for guiding treatment decisions in patients with hepatocellular carcinoma.
目的
肝癌病变特征的评估主要依赖于多层螺旋 CT（MDCT）和磁共振成像（MRI）。MDCT 存在一系列问题，如软组织对比度低和肿瘤边界误差大，导致其在肝癌中的实际应用价值有限。相比之下，钆乙氧基苯甲基二乙三胺五乙酸（Gd-EOB-DTPA）增强 MRI 比 MDCT 具有更好的软组织对比度，提高了肝癌病变的清晰度。本研究旨在探讨 MDCT 和 Gd-EOB-DTPA 增强 MRI 在肝细胞肝癌患者治疗中的差异。
方法
本研究纳入 2020 年 9 月至 2022 年 9 月在我院接受治疗的 80 例肝细胞肝癌患者，将其均分为观察组和对照组，每组 40 例。本研究旨在比较两组患者肝胆期信号指标的差异。
结果
MDCT 共检测到 89 个癌结节，Gd-EOB-DTPA 增强 MRI 共检测到 109 个癌结节。当对两种影像学方法检测到的结节数量进行统计学分析时，MDCT 和 Gd-EOB-DTPA 增强 MRI 检测到的肝细胞癌（HCC）结节数量差异具有统计学意义（P<0.05）。进一步对单肝癌结节、多肝癌结节和肝癌结节大小进行数据分析，两种影像学方法在单肝癌结节或多肝癌结节的诊断中差异有统计学意义（94.8%对 81.3%）（P<0.05）。比较差异有统计学意义（P<0.05）。
结论
Gd-EOB-DTPA 增强 MRI 对小肝癌的诊断效能较高，可为肝癌提供更准确的分期，为治疗方案的制定提供更精确的指导。因此，Gd-EOB-DTPA 增强 MRI 具有出色的诊断价值，是指导肝细胞癌患者治疗决策的宝贵工具。
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