Nicoll J M
Anaesthesia. 1986 Sep;41(9):927-30. doi: 10.1111/j.1365-2044.1986.tb12918.x.
Two patients had generalised convulsions which occurred several hours after anaesthesia supplemented with enflurane. One patient had to be treated for life threatening status epilepticus 7 hours after anaesthesia and the other had a myoclonic convulsion 17 hours after recovery from anaesthesia. Neither had any relevant pre-operative history of epilepsy or convulsions. Possible synergistic roles of the metabolite of atracurium, laudanosine, as well as of cephazolin and photic stimulation, are discussed.
两名患者在使用恩氟烷辅助麻醉数小时后出现全身性惊厥。一名患者在麻醉7小时后因危及生命的癫痫持续状态而接受治疗,另一名患者在麻醉恢复17小时后出现肌阵挛性惊厥。两人术前均无癫痫或惊厥的相关病史。文中讨论了阿曲库铵的代谢产物劳丹诺辛、头孢唑林以及光刺激可能的协同作用。