Jacome D E
Ann Ophthalmol. 1986 Oct;18(10):293-6.
Two patients with acute unilateral infarction of the medial thalamus and upper mesencephalon exhibited ipsilateral nuclear involvement of the third nerve, contralateral skew deviation with weakness of eye elevation, and monocular downbeat nystagmus. Monocular downbeat nystagmus is a rare manifestation of combined nuclear-supranuclear ophthalmoparesis that is seemingly secondary to dysfunction of cerebellar-modulated crossed oculovestibular fibers of the brachium conjunctivum, integrator neurons, or posterior commissure crossing fibers originating at the interstitial nucleus of Cajal and mediating vertical ocular reflexes.
两名患有内侧丘脑和中脑上部急性单侧梗死的患者表现出同侧动眼神经核受累、对侧斜视角偏差伴眼球上抬无力以及单眼下跳性眼球震颤。单眼下跳性眼球震颤是核上性眼肌麻痹合并核性眼肌麻痹的一种罕见表现,似乎继发于结合臂的小脑调节交叉眼前庭纤维、整合神经元或起源于 Cajal 间质核并介导垂直眼反射的后连合交叉纤维功能障碍。