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在玻利维亚(一个中低收入国家)举办了一个研讨会之后,当地对 ACOG 妊娠高血压疾病诊断指南的遵循度有所提高。

Increased adherence to ACOG diagnostic guidelines for HDP following a workshop in Bolivia, a LMIC.

机构信息

Hospital Materno-Infantil, Caja Nacional de Salud, La Paz, Bolivia.

Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado-Anschutz Medical Campus, Aurora, CO 80045, United States.

出版信息

Pregnancy Hypertens. 2023 Dec;34:19-26. doi: 10.1016/j.preghy.2023.09.004. Epub 2023 Sep 29.

Abstract

OBJECTIVES

Hypertensive disorders of pregnancy (HDP) exert a heavy mortality burden in low- to middle-income countries (LMIC). ACOG revised HDP diagnostic guidelines to improve identifying pregnancies at greatest risk but whether they are used in LMIC is unknown.

STUDY DESIGN

We held a workshop to review ACOG guidelines in La Paz, Bolivia (BO) and then reviewed prenatal, labor and delivery records for all HDP diagnoses and twice as many controls at its three largest delivery sites during the year before and the nine months after a workshop (n = 1376 cases, 2851 controls during the two periods).

MAIN OUTCOME MEASURES

HDP diagnoses, maternal, and infant characteristics.

RESULTS

Bolivian and ACOG criteria identified similar frequencies of gestational hypertension (GH) or eclampsia, but preeclampsia with severe features (sPE) was under- and preeclampsia without severe features (PE) over-reported during both periods. Increases occurred after the workshop in testing for proteinuria and the detection of abnormal laboratory values and severe hypertension in HDP women. Any adverse maternal outcome occurred more frequently after the workshop in women with BO PE or sPE diagnoses who met ACOG sPE criteria.

CONCLUSIONS

Utilization of ACOG guidelines increased following the workshop and improved identification of PE or sPE pregnancies with adverse maternal outcomes. Continued use of a CLAP perinatal form recognizing HELLP as the only kind of sPE resulted in under-reporting of sPE.

FUNDING

NIH TW010797, HD088590, HL138181.

摘要

目的

妊娠高血压疾病(HDP)在中低收入国家(LMIC)造成了沉重的死亡负担。ACOG 修订了 HDP 诊断指南,以提高对风险最大妊娠的识别能力,但这些指南在 LMIC 的使用情况尚不清楚。

研究设计

我们在玻利维亚拉巴斯(BO)举办了一个研讨会,审查 ACOG 指南,然后在研讨会前一年和后九个月,在其三个最大的分娩地点,审查所有 HDP 诊断和两倍数量的对照的产前、分娩和分娩记录(n=1376 例病例,两个时期的 2851 例对照)。

主要观察结果

HDP 诊断、产妇和婴儿特征。

结果

玻利维亚和 ACOG 标准确定了相似频率的妊娠期高血压(GH)或子痫,但严重特征性子痫前期(sPE)在两个时期均被低估,而无严重特征性子痫前期(PE)被高估。在研讨会之后,对蛋白尿检测以及 HDP 妇女异常实验室值和严重高血压的检测增加。在满足 ACOG sPE 标准的 BO PE 或 sPE 诊断的女性中,任何不良的产妇结局在研讨会后更频繁发生。

结论

研讨会后,ACOG 指南的使用增加,并改善了对具有不良产妇结局的 PE 或 sPE 妊娠的识别。继续使用一种认识到 HELLP 是唯一一种 sPE 的 CLAP 围产期表格,导致 sPE 的报告不足。

资助

NIH TW010797、HD088590、HL138181。

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