Sasaki Naoki, Saito-Sasaki Natsuko, Haruyama Sanehito, Sawada Yu
Dermatology, University of Occupational and Environmental Health, Kitakyushu, JPN.
Dermatology, Haruyama Dermatology Clinic, Gyota, JPN.
Cureus. 2023 Aug 28;15(8):e44283. doi: 10.7759/cureus.44283. eCollection 2023 Aug.
Tumors arising from burn scars are not rare but sometimes cause the rare co-existence of different tumors. However, detailed information on this topic remains largely unknown. We present a case of the co-occurrence of malignant melanoma and squamous cell carcinoma in a patient with a history of burn scars. A 73-year-old man presented with an erythematous plaque on his left lower leg that gradually turned into a tumor with ulceration. He also presented with scaly tumors at other sites within the same burn scar lesion. He had a history of burns on the left leg at the age of 20 years. After surgical resection of the tumors, histological analysis revealed that the posterior aspect of the largest tumor was malignant melanoma, and the remaining two tumors were squamous cell carcinomas, indicating the co-existence of different types of malignant skin cancers. Based on a literature review of previously published case reports, this is the first report to highlight the importance of complete skin grafts in reducing this risk.
烧伤瘢痕引发的肿瘤并不罕见，但有时会出现不同肿瘤罕见的并存情况。然而，关于这一主题的详细信息在很大程度上仍不为人知。我们报告一例有烧伤瘢痕病史的患者同时发生恶性黑色素瘤和鳞状细胞癌的病例。一名73岁男性，左小腿出现红斑性斑块，逐渐发展为伴有溃疡的肿瘤。在同一烧伤瘢痕病变的其他部位还出现了鳞屑状肿瘤。他20岁时左腿有过烧伤史。肿瘤手术切除后，组织学分析显示最大肿瘤的后部为恶性黑色素瘤，其余两个肿瘤为鳞状细胞癌，表明存在不同类型的恶性皮肤癌并存。基于对既往发表的病例报告的文献综述，这是第一份强调完整皮肤移植在降低这种风险方面重要性的报告。
