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一例原发性骨髓纤维化患者的非肝硬化门静脉高压病例。

A Case of Non-cirrhotic Portal Hypertension in a Patient With Primary Myelofibrosis Disease.

作者信息

Mangal Ruchi, Jamil Maria, Nasser Zeinab, Purtell James P

机构信息

Internal Medicine, Henry Ford Health System, Detroit, USA.

出版信息

Cureus. 2023 Aug 29;15(8):e44313. doi: 10.7759/cureus.44313. eCollection 2023 Aug.

Abstract

Idiopathic non-cirrhotic portal hypertension can emerge due to a varied spectrum of underlying and contributory factors, presenting in the form of abdominal distention as the initial symptom encountered. Often, a patient remains asymptomatic to the underlying cause and seeks medical care for their abdominal enlargement. As the portal hypertension continues to progress, ascites begins to develop due to a history of portal vein thrombosis being sufficient to increase splanchnic blood flow in a portal hypertensive pattern. We present a rare case of ascites in a non-cirrhotic patient due to portal vein thrombus with underlying myeloproliferative disease of primary myelofibrosis.

摘要

特发性非肝硬化性门静脉高压可因多种潜在和促成因素而出现,最初表现为腹胀症状。通常,患者对潜在病因无症状,而是因腹部肿大就医。随着门静脉高压持续进展,由于门静脉血栓形成史足以使内脏血流以门静脉高压模式增加,腹水开始形成。我们报告一例非肝硬化患者因门静脉血栓伴潜在原发性骨髓纤维化的骨髓增殖性疾病导致腹水的罕见病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/10535785/ec8352b82288/cureus-0015-00000044313-i01.jpg

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