Weeden Emily E, Mahil Amreesh, Huang Jeffrey
Anesthesiology Department, Moffitt Cancer Center, Tampa, USA.
Morsani College of Medicine, University of South Florida, Tampa, USA.
Cureus. 2023 Aug 29;15(8):e44318. doi: 10.7759/cureus.44318. eCollection 2023 Aug.
Rosai-Dorfman disease (RDD) is a rare condition that causes massive lymphadenopathy, most commonly in the cervical area. Cowden syndrome (CS) causes hamartomas in the skin and mucosa and predisposes individuals to various malignancies. Lhermitte-Duclos disease (LDD), or dysplastic cerebellar gangliocytoma, is often associated with CS. A 41-year-old female with all three conditions presented with abnormal uterine bleeding and endometrial intraepithelial neoplasia (EIN). Precautions should be considered when evaluating patients with RDD and CS preoperatively and during airway management owing to the potential for multisystem involvement, anatomical distortion, and difficult airways. The likelihood of having all three conditions is extremely rare.
罗萨伊-多夫曼病（RDD）是一种罕见疾病，可导致大量淋巴结病，最常见于颈部区域。考登综合征（CS）会导致皮肤和黏膜出现错构瘤，并使个体易患各种恶性肿瘤。勒米特-迪克洛病（LDD），即发育异常性小脑神经节细胞瘤，常与CS相关。一名患有这三种疾病的41岁女性出现了异常子宫出血和子宫内膜上皮内瘤变（EIN）。由于存在多系统受累、解剖结构变形和气道困难的可能性，在对患有RDD和CS的患者进行术前评估及气道管理时应考虑采取预防措施。同时患有这三种疾病的可能性极其罕见。
