Thankappan Prasanth, Gopalakrishnan Dharmarajan, Manandhar Sumita
Department of Periodontology, Dr. D. Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Pune, Maharashtra, India.
Department of Periodontology, Armed Forces Medical Colleges, Pune, Maharashtra, India.
J Indian Soc Periodontol. 2023 Sep-Oct;27(5):508-514. doi: 10.4103/jisp.jisp_7_23. Epub 2023 Sep 1.
Periodontal disease is considered to be the sixth most common complication of diabetes mellitus (DM). Antibiotics (systemic and local) enhance the outcome of conventional mechanical debridement but frequent use of antimicrobials may develop resistance to microorganisms. To overcome this complicacy, the current study assessed the effectiveness of photodynamic therapy (PDT) in chronic periodontitis patients with type 2 diabetes when used as a combination therapy to standard periodontal therapy by assessing the various clinical and glycemic parameters.
A total of 16 known cases of chronic Periodontitis patients who were suffering from type 2 DM were allocated into two groups. The test group ( = 8) was treated with standard scaling and root planing (SRP) along with PDT while the control group was treated with SRP alone. Various clinical parameters assessed were plaque index, gingival index, pocket probing depth, clinical attachment level, and Glycated hemoglobin level at baseline and 90 days after therapy.
At the end of the study, both the groups showed improvements with regard to all clinical and glycemic parameters compared to baseline. However, the test group presented statistically significant favorable results (all < 0.05).
Conventional periodontal treatment aided with PDT proved to be a beneficial therapeutic measure and effective alternative in patients with chronic periodontitis with diabetes when compared with standard periodontal therapy alone.
牙周病被认为是糖尿病(DM)第六常见的并发症。抗生素(全身和局部使用)可提高传统机械清创的效果,但频繁使用抗菌药物可能会使微生物产生耐药性。为克服这一复杂性,本研究通过评估各种临床和血糖参数,评估光动力疗法(PDT)作为标准牙周治疗的联合疗法在2型糖尿病慢性牙周炎患者中的有效性。
将1共6例已知患有2型糖尿病的慢性牙周炎患者分为两组。试验组( = 8)接受标准龈上洁治和根面平整(SRP)联合PDT治疗,而对照组仅接受SRP治疗。评估的各种临床参数包括基线时以及治疗后90天的菌斑指数、牙龈指数、牙周袋探诊深度、临床附着水平和糖化血红蛋白水平。
在研究结束时,与基线相比,两组在所有临床和血糖参数方面均有改善。然而,试验组呈现出具有统计学意义的良好结果(所有 < 0.05)。
与单独的标准牙周治疗相比,常规牙周治疗辅以PDT被证明是慢性牙周炎合并糖尿病患者的一种有益治疗措施和有效的替代方法。