Gates J R, Mireles R, Maxwell R, Sharbrough F, Forbes G
Arch Neurol. 1986 Nov;43(11):1188-91. doi: 10.1001/archneur.1986.00520110074021.
A 21-year-old man with medically intractable secondarily generalized atonic seizures underwent a corpus callosotomy on Nov 5, 1981. Though improved, the falling seizures persisted. In January 1984, magnetic resonance imaging (MRI) documented that the anterior quarter of the corpus callosum remained intact. In March, the patient underwent a completion of the callosotomy, at which time the MRI findings were corroborated. Since the second surgery, a further improvement in seizure control has been observed. Use of MRI can document both noninvasively and in vivo the extent of corpus callosotomy. The implications of selected neurophysiologic and neuropsychological findings are also discussed.
一名21岁患有药物难治性继发性全身性失张力发作的男性患者于1981年11月5日接受了胼胝体切开术。尽管有所改善，但跌倒发作仍持续存在。1984年1月，磁共振成像（MRI）显示胼胝体的前四分之一仍保持完整。3月，患者接受了胼胝体切开术的完善手术，此时MRI检查结果得到了证实。自第二次手术后，癫痫控制情况有了进一步改善。MRI的应用能够在无创和活体状态下记录胼胝体切开术的范围。文中还讨论了部分神经生理学和神经心理学研究结果的意义。
