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早产儿病房中由大肠杆菌O142 K86 H34引起的肠炎。并对“大肠杆菌肠道致病血清群”的致病性问题进行讨论(作者译)

[Enteritis due to Escherichia coli O142 K86 H34 in a ward of premature infants. With a discussion on the problem of pathogenicity of "enteropathogenic serogroups of E. coli" (author's transl)].

作者信息

Bockemühl J, Fricke G, Seeliger H P

出版信息

Zentralbl Bakteriol Orig A. 1979 Apr;243(2-3):197-206.

PMID:377855
Abstract

E. coli O142 K86 H34 has been isolated from stool specimens of five babies in a ward of premature infants. Diarrheal stools were observed in two of them; one infant temporarily failed to gain weight, and the other developed a temporary loss of weight. Smooth stools observed in the third baby as well as asymptomatic infections in two others did not affect their normal development. The outbreak lasted 15 days; the source of infection and the mode of transmission remained unknown. The pathogenesis and importance of human diarrheal disease caused by E. coli is reviewed. Enteritis of adults and children due to enteroinvasive (EIEC) and enterotoxigenic (ETEC) strains is described. The etiological role of so-called "enteropathogenic E. coli" (EPEC), rejected increasingly during the past decade, has been demonstrated again in recent studies. Routine search for EPEC is suggested in cases of infantile enteritis in hospitals and other institutions.

摘要

从一个早产儿病房的五名婴儿的粪便标本中分离出了大肠杆菌O142 K86 H34。其中两名婴儿出现腹泻性粪便;一名婴儿暂时体重未增加,另一名婴儿体重出现暂时下降。第三名婴儿的粪便正常,另外两名婴儿无症状感染,这些情况均未影响他们的正常发育。此次疫情持续了15天;感染源和传播方式仍不明。本文综述了由大肠杆菌引起的人类腹泻病的发病机制及重要性。描述了由肠侵袭性(EIEC)和产肠毒素(ETEC)菌株引起的成人和儿童肠炎。在过去十年中越来越被摒弃的所谓“肠致病性大肠杆菌”(EPEC)的病因学作用,在最近的研究中再次得到证实。建议在医院和其他机构中对婴儿肠炎病例常规筛查EPEC。

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