Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Centre for Cutaneous Research, Blizard Institute, Queen Mary University of London, London, United Kingdom.
J Cosmet Dermatol. 2023 Dec;22(12):3246-3251. doi: 10.1111/jocd.16012. Epub 2023 Oct 2.
Filler injections in the periocular region are regarded as a challenging and advanced maneuver in a high-risk area. Adverse events as malar edema due to filler treatment may occur. To evaluate the possible reasons, the ultrasound images, and medical data of patients that were prospectively referred with malar edema were evaluated.
A total of 17 patients (26 eyes) with malar edema after hyaluronic acid filler treatment were included. All cases were assessed with an 18 MHz linear ultrasound device. Exact location of the filler material was noted. Relations with clinical data were analyzed using chi-square tests.
Onset of malar edema after treatment showed a wide range from immediate (0 days) to 3 years. Most patients had an early onset N = 13 (76%), a minority showed late onset N = 4 (24%). In 23 eyes, the filler material was found to be located inside the SMAS. In 3 cases filler material was located on the periosteum of the orbital rim. After duplex-ultrasound guided filler removal, restored venous flow could be seen in the superficial and/or deep fatty layer often accompanied by flow piercing through the SMAS. Minutes after treatment, clinical improvement of malar edema was observed.
Malar edema after by filler treatments in the periocular region may be caused by veno-lymphatic compression by filler deposits.
眼周区域的填充物注射被认为是高风险区域的一项具有挑战性和先进的操作。由于填充物治疗可能会出现诸如颊部肿胀等不良反应。为了评估可能的原因,对因颊部肿胀而被前瞻性转诊的患者的超声图像和医疗数据进行了评估。
共纳入 17 名(26 只眼)接受透明质酸填充物治疗后出现颊部肿胀的患者。所有病例均使用 18MHz 线性超声设备进行评估。准确记录填充物材料的位置。使用卡方检验分析与临床数据的关系。
治疗后颊部肿胀的发病时间范围很广,从即刻(0 天)到 3 年不等。大多数患者发病较早,N=13(76%),少数患者发病较晚,N=4(24%)。在 23 只眼中,填充物材料位于 SMAS 内。在 3 例中,填充物材料位于眶缘的骨膜上。在双功能超声引导下去除填充物后,通常在浅层和/或深层脂肪层中可以看到恢复的静脉血流,并且血流穿过 SMAS。治疗后几分钟,观察到颊部肿胀的临床改善。
眼周区域填充物治疗后出现颊部肿胀可能是由于填充物沉积引起的静脉淋巴压迫所致。