Department of Radiology, Lanzhou University Second Hospital, Chengguan District, Lanzhou, 730030, China.
Second Clinical School, Lanzhou University, Lanzhou, 730030, China.
Abdom Radiol (NY). 2023 Dec;48(12):3661-3676. doi: 10.1007/s00261-023-04046-1. Epub 2023 Oct 3.
Effective neoadjuvant chemotherapy (NAC) can improve the survival of patients with locally progressive gastric cancer, but chemotherapeutics do not always exhibit good efficacy in all patients. Therefore, accurate preoperative evaluation of the effect of neoadjuvant therapy and the appropriate selection of surgery time to minimize toxicity and complications while prolonging patient survival are key issues that need to be addressed. This paper reviews the role of three imaging methods, morphological, functional, radiomics, and artificial intelligence (AI)-based imaging, in evaluating NAC pathological reactions for gastric cancer. In addition, the advantages and disadvantages of each method and the future application prospects are discussed.
有效的新辅助化疗(NAC)可以改善局部进展期胃癌患者的生存,但化疗并非在所有患者中均显示出良好的疗效。因此,准确地术前评估新辅助治疗的效果,并选择合适的手术时间,以最大限度地减少毒性和并发症,同时延长患者的生存时间,是需要解决的关键问题。本文综述了三种影像学方法(形态学、功能学、影像组学和基于人工智能(AI)的影像学)在评估胃癌 NAC 病理反应中的作用。此外,还讨论了每种方法的优缺点和未来的应用前景。