Moghadaskhou Fatemeh, Eivazzadeh-Keihan Reza, Sadat Zahra, Tadjarodi Azadeh, Maleki Ali
Research Laboratory of Inorganic Materials Synthesis, Department of Chemistry, Iran University of Science and Technology, Tehran, 16846-13114, Iran.
Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, 16846-13114, Iran.
Sci Rep. 2023 Oct 3;13(1):16584. doi: 10.1038/s41598-023-43869-2.
A novel catalyst was fabricated in this study based on zirconium MOF modified with pyridine carboxaldehyde in a solvothermal reaction, embedded with cerium. In order to confirm the catalyst structure, various characterization techniques, including FTIR, Far IR, EDX, XRD, TGA, FE-SEM, ICP, and BET analyses, were employed. The results indicated that the UiO-66-Pyca-Ce (III) catalyst had a Langmuir surface area of 501.63 m/g, a pore volume of 0.28 cm/g, and a pore size of 2.27 nm. To study catalytic activity, a sequential approach of Knoevenagel condensation and Michael addition was used to synthesize various polyhydroquinoline derivatives. The reaction took place at ambient temperature. The UiO-66-Pyca-Ce (III) catalyst demonstrated high efficacy (90%) and reusability in asymmetric synthesis of polyhydroquinoline derivatives for several reasons, including the possession of three Lewis acid activation functions.
在本研究中，通过溶剂热反应制备了一种基于吡啶甲醛修饰的锆基金属有机框架（MOF）并嵌入铈的新型催化剂。为了确定催化剂结构，采用了多种表征技术，包括傅里叶变换红外光谱（FTIR）、远红外光谱（Far IR）、能量散射X射线光谱（EDX）、X射线衍射（XRD）、热重分析（TGA）、场发射扫描电子显微镜（FE-SEM）、电感耦合等离子体质谱（ICP）和比表面积分析（BET）。结果表明，UiO-66-Pyca-Ce（III）催化剂的朗缪尔表面积为501.63 m²/g，孔体积为0.28 cm³/g，孔径为2.27 nm。为了研究催化活性，采用Knoevenagel缩合和迈克尔加成的连续方法合成了各种多氢喹啉衍生物。反应在室温下进行。UiO-66-Pyca-Ce（III）催化剂在多氢喹啉衍生物的不对称合成中表现出高效性（90%）和可重复使用性，原因包括具有三种路易斯酸活化功能。
