• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Co-housing with Alzheimer's disease mice induces changes in gut microbiota and impairment of learning and memory in control mice.

作者信息

Li Jun, Shan Weiran, Zuo Zhiyi

机构信息

Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.

出版信息

CNS Neurosci Ther. 2024 Apr;30(4):e14491. doi: 10.1111/cns.14491. Epub 2023 Oct 3.

DOI:10.1111/cns.14491
PMID:37789692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11017403/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da36/11017403/9fff8a3a3fa8/CNS-30-e14491-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da36/11017403/9fff8a3a3fa8/CNS-30-e14491-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da36/11017403/9fff8a3a3fa8/CNS-30-e14491-g002.jpg

相似文献

1
Co-housing with Alzheimer's disease mice induces changes in gut microbiota and impairment of learning and memory in control mice.与患有阿尔茨海默病的小鼠共同饲养会导致对照小鼠肠道微生物群发生变化以及学习和记忆受损。
CNS Neurosci Ther. 2024 Apr;30(4):e14491. doi: 10.1111/cns.14491. Epub 2023 Oct 3.
2
Alterations of Spatial Memory and Gut Microbiota Composition in Alzheimer's Disease Triple-Transgenic Mice at 3, 6, and 9 Months of Age.阿尔茨海默病三转基因小鼠在 3、6 和 9 个月大时的空间记忆和肠道微生物组成的改变。
Am J Alzheimers Dis Other Demen. 2023 Jan-Dec;38:15333175231174193. doi: 10.1177/15333175231174193.
3
Alzheimer's Disease Histological and Behavioral Manifestations in Transgenic Mice Correlate with Specific Gut Microbiome State.转基因小鼠中的阿尔茨海默病组织学和行为表现与特定肠道微生物群状态相关。
J Alzheimers Dis. 2017;56(1):385-390. doi: 10.3233/JAD-160884.
4
Bidirectional interactions between curcumin and gut microbiota in transgenic mice with Alzheimer's disease.阿尔茨海默病转基因小鼠中姜黄素与肠道微生物群的双向相互作用。
Appl Microbiol Biotechnol. 2020 Apr;104(8):3507-3515. doi: 10.1007/s00253-020-10461-x. Epub 2020 Feb 24.
5
Gut amyloid-β induces cognitive deficits and Alzheimer's disease-related histopathology in a mouse model.肠道淀粉样β蛋白在小鼠模型中诱发认知缺陷及阿尔茨海默病相关的组织病理学变化。
J Physiol. 2021 Jan;599(1):15-16. doi: 10.1113/JP280624. Epub 2020 Oct 6.
6
Transfer of a healthy microbiota reduces amyloid and tau pathology in an Alzheimer's disease animal model.健康微生物群转移可减少阿尔茨海默病动物模型中的淀粉样蛋白和 tau 病理。
Gut. 2020 Feb;69(2):283-294. doi: 10.1136/gutjnl-2018-317431. Epub 2019 Aug 30.
7
Time to test antibacterial therapy in Alzheimer's disease.是时候在阿尔茨海默病中测试抗菌疗法了。
Brain. 2019 Oct 1;142(10):2905-2929. doi: 10.1093/brain/awz244.
8
Injection of amyloid-β to lateral ventricle induces gut microbiota dysbiosis in association with inhibition of cholinergic anti-inflammatory pathways in Alzheimer's disease.向侧脑室注射淀粉样蛋白-β会引起阿尔茨海默病中胆碱能抗炎途径抑制相关的肠道微生物群落失调。
J Neuroinflammation. 2022 Sep 28;19(1):236. doi: 10.1186/s12974-022-02599-4.
9
Gut microbiome composition may be an indicator of preclinical Alzheimer's disease.肠道微生物组的组成可能是临床前阿尔茨海默病的一个指标。
Sci Transl Med. 2023 Jun 14;15(700):eabo2984. doi: 10.1126/scitranslmed.abo2984.
10
Antibiotic-induced gut microbiota depletion from early adolescence exacerbates spatial but not recognition memory impairment in adult male C57BL/6 mice with Alzheimer-like disease.抗生素诱导的早青春期肠道微生物组耗竭会加剧具有阿尔茨海默病样疾病的成年雄性 C57BL/6 小鼠的空间记忆损伤，但不会加剧其识别记忆损伤。
Brain Res Bull. 2021 Nov;176:8-17. doi: 10.1016/j.brainresbull.2021.08.004. Epub 2021 Aug 12.

引用本文的文献

1
Progressive gut microbiota shifts and functional alterations across aging stages and frailty in mice.衰老阶段及小鼠虚弱状态下肠道微生物群的渐进性变化与功能改变
iScience. 2025 Jun 23;28(7):112985. doi: 10.1016/j.isci.2025.112985. eCollection 2025 Jul 18.

本文引用的文献

1
Transplantation of fecal microbiota from APP/PS1 mice and Alzheimer's disease patients enhanced endoplasmic reticulum stress in the cerebral cortex of wild-type mice.移植APP/PS1小鼠和阿尔茨海默病患者的粪便微生物群会增强野生型小鼠大脑皮质中的内质网应激。
Front Aging Neurosci. 2022 Jul 28;14:858130. doi: 10.3389/fnagi.2022.858130. eCollection 2022.
2
Gut Microbiota Dysbiosis Induced by Decreasing Endogenous Melatonin Mediates the Pathogenesis of Alzheimer's Disease and Obesity.内源性褪黑素减少引起的肠道微生物失调介导阿尔茨海默病和肥胖的发病机制。
Front Immunol. 2022 May 10;13:900132. doi: 10.3389/fimmu.2022.900132. eCollection 2022.
3
Preoperative environment enrichment preserved neuroligin 1 expression possibly via epigenetic regulation to reduce postoperative cognitive dysfunction in mice.
术前环境丰富可能通过表观遗传调控来保存神经黏附分子 1 的表达，从而减少小鼠术后认知功能障碍。
CNS Neurosci Ther. 2022 Apr;28(4):619-629. doi: 10.1111/cns.13777. Epub 2021 Dec 9.
4
Transplantation of gut microbiota derived from Alzheimer's disease mouse model impairs memory function and neurogenesis in C57BL/6 mice.来自阿尔茨海默病小鼠模型的肠道微生物群移植会损害 C57BL/6 小鼠的记忆功能和神经发生。
Brain Behav Immun. 2021 Nov;98:357-365. doi: 10.1016/j.bbi.2021.09.002. Epub 2021 Sep 6.
5
Paraventricular thalamic nucleus plays a critical role in consolation and anxious behaviors of familiar observers exposed to surgery mice.室旁丘脑核在暴露于手术小鼠的熟悉观察者的安慰和焦虑行为中起关键作用。
Theranostics. 2021 Feb 6;11(8):3813-3829. doi: 10.7150/thno.45690. eCollection 2021.
6
Gut Microbiome Features of Chinese Patients Newly Diagnosed with Alzheimer's Disease or Mild Cognitive Impairment.中国阿尔茨海默病或轻度认知障碍新诊断患者的肠道微生物组特征。
J Alzheimers Dis. 2021;80(1):299-310. doi: 10.3233/JAD-201040.
7
Dysbiosis, gut barrier dysfunction and inflammation in dementia: a pilot study.痴呆症中的菌群失调、肠道屏障功能障碍和炎症：一项初步研究。
BMC Geriatr. 2020 Jul 20;20(1):248. doi: 10.1186/s12877-020-01644-2.
8
The similar past pain experience evokes both observational contagious pain and consolation in stranger rat observers.相似的过去疼痛经历会在陌生大鼠观察者身上引发观察性的传染性疼痛和安慰反应。
Neurosci Lett. 2020 Mar 23;722:134840. doi: 10.1016/j.neulet.2020.134840. Epub 2020 Feb 17.
9
The relationship between the gut microbiome and mild cognitive impairment in patients without dementia: a cross-sectional study conducted in Japan.肠道微生物组与无痴呆症患者轻度认知障碍的关系：在日本进行的一项横断面研究。
Sci Rep. 2019 Dec 18;9(1):19227. doi: 10.1038/s41598-019-55851-y.
10
Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression.低聚甘露糖通过治疗重塑肠道微生物群，抑制肠道细菌氨基酸诱导的神经炎症来抑制阿尔茨海默病的进展。
Cell Res. 2019 Oct;29(10):787-803. doi: 10.1038/s41422-019-0216-x. Epub 2019 Sep 6.