Alvi Ali Tariq, Santiago Luis E, Nadeem Zahid, Chaudhry Ali
Internal Medicine, HCA Florida Northwest Hospital, Margate, USA.
Critical Care, HCA Florida Northwest Hospital, Margate, USA.
Cureus. 2023 Sep 1;15(9):e44544. doi: 10.7759/cureus.44544. eCollection 2023 Sep.
Hereditary hemochromatosis (HH) is an inherited disorder in which organ damage and other clinical manifestations are commonly seen in patients with a homozygous mutation involving of the gene, causing increased iron absorption in the intestine. The liver is the primary site of iron deposition, and excessive iron overload can eventually lead to hepatic cirrhosis. Patients who drink significant amounts of alcohol are more likely to develop cirrhosis, and in females, it is commonly seen after menopause. We describe a young female with hereditary hemochromatosis who developed fulminant hepatic failure with minimal alcohol consumption at age 25.
遗传性血色素沉着症（HH）是一种遗传性疾病，纯合子突变涉及该基因的患者常出现器官损伤和其他临床表现，导致肠道铁吸收增加。肝脏是铁沉积的主要部位，铁过载最终可导致肝硬化。大量饮酒的患者更易发生肝硬化，女性患者常在绝经后出现。我们描述了一名患有遗传性血色素沉着症的年轻女性，她在25岁时仅少量饮酒就发生了暴发性肝衰竭。
