• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Prevalence of the fragile X syndrome in an institution for the mentally handicapped.

作者信息

Primrose D A, el-Matmati R, Boyd E, Gosden C, Newton M

出版信息

Br J Psychiatry. 1986 Jun;148:655-7. doi: 10.1192/bjp.148.6.655.

DOI:10.1192/bjp.148.6.655
PMID:3779244
Abstract

In an investigation to find the prevalence of the fragile X (Martin Bell) syndrome in a mental handicap hospital, chromosomal investigations were carried out in 196 males selected out of a total of 512, and also in 20 female patients who were related to some of the selected males. Fragile X cells were found in 41 of the males and two of the females; in 21 of the males it was associated with macro-orchidism. The overall prevalence in the hospital for males (8.0%) ranks this syndrome next in importance to Down's syndrome as a known cause for mental handicap.

摘要

相似文献

1
Prevalence of the fragile X syndrome in an institution for the mentally handicapped.
Br J Psychiatry. 1986 Jun;148:655-7. doi: 10.1192/bjp.148.6.655.
2
Screening of mentally retarded males for macro-orchidism and the fragile X chromosome.
Am J Med Genet. 1983 Aug;15(4):631-5. doi: 10.1002/ajmg.1320150414.
3
The Martin-Bell syndrome in South Africa.南非的马丁 - 贝尔综合征。
Am J Med Genet. 1986 Jan-Feb;23(1-2):597-610. doi: 10.1002/ajmg.1320230154.
4
Martin-Bell syndrome in Greece, with report of another 47,XXY fragile X patient.希腊的马丁-贝尔综合征，附另一例47,XXY脆性X患者的报告。
Am J Med Genet. 1988 Dec;31(4):735-9. doi: 10.1002/ajmg.1320310403.
5
The fragile X in Sicily: an epidemiological survey.西西里岛的脆性X综合征：一项流行病学调查。
Am J Med Genet. 1988 May-Jun;30(1-2):665-72. doi: 10.1002/ajmg.1320300167.
6
Prevalence of mental retardation related to fragile X syndrome and other chromosomal abnormalities in the Republic of San Marino.
Dev Med Child Neurol. 1988 Oct;30(5):646-9. doi: 10.1111/j.1469-8749.1988.tb04803.x.
7
Population incidence and segregation ratios in the Martin-Bell syndrome.马丁-贝尔综合征的群体发病率和分离比率。
Am J Med Genet. 1986 Jan-Feb;23(1-2):573-80. doi: 10.1002/ajmg.1320230151.
8
Fragile X mental retardation: prevalence in a group of institutionalized patients in Italy and description of a novel EEG pattern.
Am J Med Genet. 1986 Jan-Feb;23(1-2):589-95. doi: 10.1002/ajmg.1320230153.
9
Neurological findings in patients with the fragile-X syndrome.脆性X综合征患者的神经学表现
J Neurol Neurosurg Psychiatry. 1985 Feb;48(2):150-3. doi: 10.1136/jnnp.48.2.150.
10
Institutional prevalence of fragile X syndrome.
Lancet. 1983 Dec 17;2(8364):1427. doi: 10.1016/s0140-6736(83)90963-7.

引用本文的文献

1
Event-related potential alterations in fragile X syndrome.脆性X综合征中的事件相关电位改变
Front Hum Neurosci. 2012 Sep 24;6:264. doi: 10.3389/fnhum.2012.00264. eCollection 2012.
2
Fragile X syndrome among children with mental retardation.智力迟钝儿童中的脆性X综合征。
Indian J Pediatr. 1996 Jul-Aug;63(4):533-8. doi: 10.1007/BF02905729.
3
Brief report: low frequency of the fragile X syndrome among Japanese autistic subjects.简短报告：日本自闭症患者中脆性X综合征的低发病率
J Autism Dev Disord. 1993 Mar;23(1):201-9. doi: 10.1007/BF01066429.
4
Frequency of the fragile X syndrome in institutionalized mentally retarded females in Japan.日本收容机构中智力迟钝女性的脆性X综合征发病率
Hum Genet. 1987 Aug;76(4):344-7. doi: 10.1007/BF00272442.
5
Ten families with fragile X syndrome: linkage relationships with four DNA probes from distal Xq.十个患有脆性X综合征的家庭：与来自Xq远端的四个DNA探针的连锁关系
Hum Genet. 1987 Jun;76(2):165-72. doi: 10.1007/BF00284915.
6
Intelligence and cognitive profile in the fra(X) syndrome: a longitudinal study in 18 fra(X) boys.脆性X综合征的智力和认知概况：对18名脆性X综合征男孩的纵向研究。
J Med Genet. 1989 Jul;26(7):443-6. doi: 10.1136/jmg.26.7.443.
7
Chromosome studies of males in an institution for the mentally handicapped.一所智障人士机构中男性的染色体研究。
J Med Genet. 1989 Jun;26(6):379-81. doi: 10.1136/jmg.26.6.379.