巴西亚马逊地区一家三级转诊医院血流感染的微生物分布及抗菌药物耐药模式。
Microbiological profile of bloodstream infections and antimicrobial resistance patterns at a tertiary referral hospital in Amazon, Brazil.
机构信息
Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Laboratório de Bacteriologia, Manaus, AM, Brasil.
Universidade Federal do Amazonas, Programa de Pós-graduação em Biotecnologia, Manaus, AM, Brasil.
出版信息
Rev Soc Bras Med Trop. 2023 Sep 22;56:e03822023. doi: 10.1590/0037-8682-0382-2023. eCollection 2023.
BACKGROUND
Bloodstream infections (BSI) are a global health issue, leading to high mortality and morbidity among hospitalized patients.
METHODS
A retrospective, observational and descriptive study was conducted by reviewing blood culture records collected from patients with suspected BSI, between January 2017 and December 2019.
RESULTS
The most frequent antimicrobial resistant (AMR) pathogens were methicillin-resistantStaphylococcus aureus(MRSA) (40%), methicillin-resistantS. epidermidis (MRSE) (9.5%), and extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae (35.3%).
CONCLUSIONS
Our findings underscore the importance of continued vigilance and advocate for the rational use of antimicrobial agents.
背景
血流感染（BSI）是一个全球性的健康问题，导致住院患者的死亡率和发病率居高不下。
方法
通过回顾 2017 年 1 月至 2019 年 12 月期间疑似血流感染患者的血培养记录，进行了一项回顾性、观察性和描述性研究。
结果
最常见的抗菌药物耐药（AMR）病原体是耐甲氧西林金黄色葡萄球菌（MRSA）（40%）、耐甲氧西林表皮葡萄球菌（MRSE）（9.5%）和产超广谱β-内酰胺酶（ESBL）的肠杆菌科（35.3%）。
结论
我们的研究结果强调了持续监测和合理使用抗菌药物的重要性。
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