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一项关于负压伤口疗法与传统伤口疗法在失活和感染性伤口术后处理中的效率的单中心前瞻性研究。

A single-center prospective study on the efficiency of negative pressure wound therapy versus conventional wound therapy in the postoperative management of devitalized and infected wounds.

出版信息

Ann Ital Chir. 2023;94:411-418.

PMID:37794810
Abstract

INTRODUCTION

In this study, we aim to present the benefits of using negative pressure wound therapy, particularly with respect to the speed up of recovery time of devitalized and infected post-operative wounds, cost-effectiveness of local healing, pain relief during treatment, and returning to work and resuming normal daily activities at an earlier time.

MATERIALS AND METHODS

This was a prospective study performed in General Surgery Clinic, between 2016-2018. The study comprised 67 patients divided into two groups: A (29 patients who underwent negative pressure wound therapy) and B (38 patients who underwent conventional wound therapy).

RESULTS

The average age of patients included in group A was 64.2 ± 12.3 years and in group B, 63.2 ± 9.7 years (p=0.440). The wounds were located on the foot, thigh, abdomen, and other areas, and the average length of stay in hospital was 33 ± 18 days for group A versus 17 ± 14 days for group B (p=0.042) but with an average local healing time of 12 ± 5 days in group A versus 44 ± 17 days in group B (p<0.001). The average cost of hospitalization was higher in group A: 17,868 ± 9,560 RON (3,834 ± 2,051 euros) compared to group B: 6,025 ± 4,137 RON (1,292 ± 887 euros) (p=0.443) but the average cost of local healing was lower in group A: 5,437 ± 2,238 RON (1,166 ± 480 euro) compared to group B: 6,840 ± 3,520 RON (1,467 ± 755 euro) (p=0.005).

CONCLUSIONS

The treatment of devitalized and infected post-operative wounds by using negative pressure wound therapy reduces local and complete healing time by approximately 30%, local healing costs by 26%, and allows better pain management during treatment with minimal complications.

KEY WORDS

Negative pressure wound Therapy, Conventional wound therapy, Local healing, average cost.

摘要

简介

在这项研究中,我们旨在介绍负压伤口治疗的益处,特别是在加速失活和感染的术后伤口的恢复时间、局部愈合的成本效益、治疗过程中的疼痛缓解以及更早地返回工作和恢复正常日常活动方面。

材料和方法

这是一项 2016 年至 2018 年在普外科诊所进行的前瞻性研究。该研究包括 67 名患者,分为两组:A 组(29 名接受负压伤口治疗的患者)和 B 组(38 名接受常规伤口治疗的患者)。

结果

A 组患者的平均年龄为 64.2 ± 12.3 岁,B 组为 63.2 ± 9.7 岁(p=0.440)。伤口位于足部、大腿、腹部和其他部位,A 组患者的平均住院时间为 33 ± 18 天,B 组为 17 ± 14 天(p=0.042),但 A 组的平均局部愈合时间为 12 ± 5 天,B 组为 44 ± 17 天(p<0.001)。A 组的平均住院费用较高:17868 ± 9560 罗马尼亚列伊(3834 ± 2051 欧元),而 B 组为 6025 ± 4137 罗马尼亚列伊(1292 ± 887 欧元)(p=0.443),但 A 组的平均局部愈合费用较低:5437 ± 2238 罗马尼亚列伊(1166 ± 480 欧元),而 B 组为 6840 ± 3520 罗马尼亚列伊(1467 ± 755 欧元)(p=0.005)。

结论

使用负压伤口治疗失活和感染的术后伤口可将局部和完全愈合时间缩短约 30%,局部愈合成本降低 26%,并在治疗过程中更好地管理疼痛,同时并发症最小。

关键词

负压伤口治疗、常规伤口治疗、局部愈合、平均成本。

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