“婴儿忍者”（即时行动消除肾毒性损伤）预防新生儿药物性肾损伤的实施策略
Implementation Strategies for Baby NINJA (Nephrotoxic Injury Negated by Just-in-Time Action) to Prevent Neonatal Medication-Induced Kidney Injury.
作者信息
Stone Sadie B, Bisaccia Elizabeth, Zakhary Mary Soliman, Bashqoy Ferras, Wagner Deborah, Stoops Christine
机构信息
Department of Pharmacy (SBS), Children's of Alabama, Birmingham, AL.
Department of Pharmacy (EB), Advocate Aurora Health, Park Ridge, IL.
出版信息
J Pediatr Pharmacol Ther. 2023;28(4):287-296. doi: 10.5863/1551-6776-28.4.287. Epub 2023 Aug 9.
Abstract
Acute kidney injury (AKI) is a common complication among patients admitted to the neonatal intensive care unit. Nephrotoxic medications (NTMs) are known to increase the incidence of AKI, but the use of these -medications is often unavoidable. Baby NINJA (Nephrotoxic Injury Negated by Just-in-Time Action) is a -quality improvement (QI) project that may be implemented at individual institutions and aims to systematically identify AKI in neonates and infants receiving NTMs. The purpose of this review is to describe nephrotoxic AKI in the neonatal population, introduce the Baby NINJA QI project and its potential to reduce neonatal AKI, and outline strategies for effective implementation of Baby NINJA.
摘要
急性肾损伤（AKI）是新生儿重症监护病房收治患者中常见的并发症。已知肾毒性药物（NTMs）会增加AKI的发生率，但这些药物的使用往往不可避免。“婴儿忍者”（及时行动消除肾毒性损伤）是一个质量改进（QI）项目，可在各机构实施，旨在系统识别接受NTMs治疗的新生儿和婴儿中的AKI。本综述的目的是描述新生儿群体中的肾毒性AKI，介绍“婴儿忍者”QI项目及其降低新生儿AKI的潜力，并概述有效实施“婴儿忍者”项目的策略。
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