Suppr超能文献

分析弹性血管壁颈动脉中分数阶麦克斯韦幂律流体的周期性脉动血流。

Analysis of periodic pulsating blood flow of fractional Maxwell power-law fluid in carotid artery with elastic vessel wall.

机构信息

School of Science, Beijing University of Civil Engineering and Architecture, Beijing, China.

Beijing Key Laboratory of Functional Materials for Building Structure and Environment Remediation, Beijing University of Civil Engineering and Architecture, Beijing, China.

出版信息

Comput Methods Biomech Biomed Engin. 2024 Oct;27(13):1845-1857. doi: 10.1080/10255842.2023.2262667. Epub 2023 Oct 5.

Abstract

Hemodynamic analysis reveals a highly significant effect on the prevention, diagnosis, and treatment of human vascular diseases. This article goes deeply into the periodic pulsatile blood flow in the carotid artery with an elastic vessel wall. In view of blood rheological experimental data, the constitutive equation of fractional Maxwell power-law fluid with yield stress, which can describe the four characteristics of yield stress, viscoelasticity, shear thinning, and thixotropy is established. Meanwhile, drawing support from the data of pulsatile flow, the finite Fourier series of pressure gradient with a period of 1 s has been proposed. Leading into Hooke's law can build the fluid-structure coupling boundary condition of blood flow and elastic vessel wall. The numerical solutions are got hold of finite difference method integrated with the newly developed L1-algorithm, and their convergence and stability of which are verified. The axial velocities of blood under different constitutive relationships are compared. The results throw light that other constitutive relationships underestimate the velocity of blood. Furthermore, the flow rate and wall shear stress on different fluid are calculated. It can be concluded that compared with Bingham fluid, the maximum and minimum flow rate/wall shear stress of fractional Maxwell power-law fluid with yield stress increases by 19% and 32%, respectively. The flow rate lags behind the pressure gradient and has time delay effect, on the contrary, the velocity of blood vessel wall is keeping pace with the pressure gradient. The effects of relevant physical parameters on velocity are discussed. In addition, the spatiotemporal distribution of blood flow in cerebral artery and femoral artery are analyzed.

摘要

血流动力学分析在人类血管疾病的预防、诊断和治疗方面具有重要意义。本文深入研究了具有弹性血管壁的颈动脉中的周期性脉动血流。根据血液流变学实验数据,建立了具有屈服应力的分数阶 Maxwell 幂律流体本构方程,该方程可以描述屈服应力、粘弹性、剪切稀化和触变性四个特征。同时,根据脉动流数据,提出了周期为 1s 的压力梯度有限傅里叶级数。引入胡克定律可以建立血流和弹性血管壁的流固耦合边界条件。采用新开发的 L1 算法结合有限差分法得到数值解,并验证了其收敛性和稳定性。比较了不同本构关系下的血液轴向速度。结果表明,其他本构关系低估了血液的速度。此外,计算了不同流体的流量和壁面切应力。结果表明,与宾汉流体相比,具有屈服应力的分数阶 Maxwell 幂律流体的最大和最小流量/壁面切应力分别增加了 19%和 32%。流量落后于压力梯度,具有时滞效应,相反,血管壁的速度与压力梯度同步。讨论了相关物理参数对速度的影响。此外,还分析了大脑动脉和股动脉血流的时空分布。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验