U.S. Department of Veteran Affairs, Veterans Affairs Boston Healthcare System, Boston, Massachusetts.
Department of Psychiatry, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts.
J Stud Alcohol Drugs. 2024 Jan;85(1):51-61. doi: 10.15288/jsad.23-00094. Epub 2023 Oct 3.
Alcohol-related problems (e.g., physical, interpersonal, intrapersonal, impulse control, social responsibility) can have an impact on posttraumatic stress disorder (PTSD) symptoms during treatment. Evidence-based online self-help tools exist to target alcohol use and related problems and co-occurring PTSD symptoms. It is unknown to what degree individuals with varying alcohol-related problems respond differently to web-based interventions for hazardous alcohol use and PTSD. The current study evaluated specific alcohol-related problems as potential moderators of PTSD symptom changes during the VetChange online intervention while controlling for average daily alcohol use, gender, race, and age.
We conducted a secondary analysis of a randomized controlled trial that included 600 post-9/11 veterans (518 men and 82 women). Mixed-effects regression models of alcohol-related problems on PTSD severity scores over time were performed separately in an initial intervention group (IIG; = 404) and a delayed intervention group (DIG; = 196) that was used as a comparison condition.
Interpersonal problems emerged as a moderator of PTSD symptom changes in IIG such that veterans endorsing greater interpersonal problems demonstrated larger reductions in PTSD symptoms throughout VetChange. There were no significant moderation effects in DIG. Non-White veterans reported significantly higher PTSD symptoms during VetChange. Post hoc analyses indicated that veterans with higher interpersonal problems were more likely to engage in online intervention content focused on identifying high-risk drinking situations and coping with symptoms.
Findings imply that veterans reporting alcohol-related interpersonal problems may benefit the most from, and be more motivated to use, online interventions for hazardous alcohol use and PTSD symptoms.
酒精相关问题(如身体、人际、内在、冲动控制、社会责任)可能会影响治疗过程中的创伤后应激障碍(PTSD)症状。现已有基于证据的在线自助工具可用于针对酒精使用和相关问题以及共病 PTSD 症状。目前尚不清楚具有不同酒精相关问题的个体对基于网络的危险饮酒和 PTSD 干预的反应程度有何不同。本研究评估了特定的酒精相关问题作为 VetChange 在线干预期间 PTSD 症状变化的潜在调节因素,同时控制了平均每日饮酒量、性别、种族和年龄。
我们对一项随机对照试验进行了二次分析,该试验纳入了 600 名 9/11 后退伍军人(518 名男性和 82 名女性)。分别在初始干预组(IIG;n=404)和延迟干预组(DIG;n=196)中进行了混合效应回归模型,以评估酒精相关问题与 PTSD 严重程度评分随时间的变化关系,DIG 作为比较条件。
人际问题在 IIG 中作为 PTSD 症状变化的调节因素出现,即人际问题得分较高的退伍军人在 VetChange 过程中 PTSD 症状的减轻幅度更大。在 DIG 中没有显著的调节作用。非白种退伍军人在 VetChange 期间报告的 PTSD 症状明显更高。事后分析表明,人际问题得分较高的退伍军人更有可能参与针对危险饮酒和 PTSD 症状的在线干预内容。
研究结果表明,报告酒精相关人际问题的退伍军人可能从针对危险饮酒和 PTSD 症状的在线干预中获益最多,并且更有动力使用此类干预。