Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
PLoS Negl Trop Dis. 2023 Oct 5;17(10):e0011686. doi: 10.1371/journal.pntd.0011686. eCollection 2023 Oct.
Podoconiosis (endemic non-filarial elephantiasis) is a chronic disease characterized by the development of persistent swelling of plantar foot initially; which progresses to the dorsal foot and lower leg slowly or in a number of acute episodes to reach the knee. About 4 million people are said to be affected by the disease worldwide and it is deemed a serious public health problem in at least 10 African countries including Ethiopia. Therefore this study aimed to identify the determinants of podoconiosis among residence in Machakel district.
Unmatched case control study design was conducted at Machakel district from August 30 to September 30, 2022. The sample size calculated using Epi-info software yielded 211 controls and 106 cases (317 study participants). Simple random sampling technique was used to select the cases using registration books of the district. Data were entered to Epi info version 7 and exported to SPSS version 22 for statistical analysis. Binary logistic regression was used to identify explanatory variables.
A total of 312 study participants (104 cases and 208 controls) were included giving a response rate of 98.42%. Bare foot (AOR, 5.83 [95% CI: 2.34-14.50]), female sex (AOR, 4.25 [95% CI: 2.22-8.14]), family history of podoconiosis (AOR: 3.01(95% CI: 1.41-6.42) and age group 41-60 (AOR: 5.05(95% CI: 2.35-10.83), and 61-80 AOR 15.74 95% CI: (5.56-44.55) were determinants of Podoconiosis.
Barefoot, sex, family history of podoconiosis and age were determinants of Podoconiosis. District health office should encourage at risk populations especially older people and individuals with family history of podoconiosis about shoe wearing practice all the time and not to expose their skin and feet.
Podoconiosis(地方性非血丝丝虫性象皮病)是一种慢性疾病,其特征为足底最初出现持续性肿胀;然后缓慢地或在多次急性发作中扩展到脚背和小腿,直至达到膝盖。据世界卫生组织称,全世界约有 400 万人受到该病的影响,该病在埃塞俄比亚等至少 10 个非洲国家被视为严重的公共卫生问题。因此,本研究旨在确定 Machakel 区 Podoconiosis 的决定因素。
2022 年 8 月 30 日至 9 月 30 日,在 Machakel 区进行了病例对照研究设计。使用 Epi-info 软件计算得出的样本量为 211 名对照和 106 名病例(317 名研究参与者)。使用区登记册采用简单随机抽样技术选择病例。数据输入 Epi info 版本 7 并导出到 SPSS 版本 22 进行统计分析。采用二元逻辑回归识别解释变量。
共有 312 名研究参与者(104 例病例和 208 名对照)被纳入研究,应答率为 98.42%。赤脚(OR,5.83[95%CI:2.34-14.50])、女性(OR,4.25[95%CI:2.22-8.14])、家族 Podoconiosis 病史(OR:3.01[95%CI:1.41-6.42])和 41-60 岁年龄组(OR:5.05[95%CI:2.35-10.83])、61-80 岁年龄组(OR:15.74[95%CI:5.56-44.55])是 Podoconiosis 的决定因素。
赤脚、性别、家族 Podoconiosis 病史和年龄是 Podoconiosis 的决定因素。区卫生办公室应鼓励高危人群,特别是老年人和有 Podoconiosis 家族史的个体,始终穿着鞋子,并避免暴露皮肤和脚部。