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用于皮瓣监测的光学仪器的设计与测试。

Design and testing of an optical instrument for skin flap monitoring.

机构信息

Department of Electronics Technology, Universidad Carlos III de Madrid, 28911, Leganes, Madrid, Spain.

Departamento de Cirugía Plástica, Reparadora y Quemados, Hospital Universitario La Paz, 28046, Madrid, Spain.

出版信息

Sci Rep. 2023 Oct 5;13(1):16778. doi: 10.1038/s41598-023-44017-6.

Abstract

Flap procedures are complex surgical tools widely used in reconstructive surgery. Flap ischemia is one of the most dangerous complications, both during the surgical procedure and during the patient's recovery, which can quickly lead to tissue necrosis (flap loss) with serious medical and psychological consequences. Today, bedside clinical assessment remains the gold standard for flap monitoring, but timely detection of flap ischemia is a difficult and challenging task, so auxiliary techniques are needed to support flap monitoring. Here we present a prototype of a new optical diagnostic tool, based on visible light absorption in diffuse reflectance spectroscopy, for non-invasive, continuous, real-time monitoring of flaps. The proposed approach is assessed by monitoring flap ischemic scenarios induced on pig animal models. The results obtained support that the proposed approach has great potential, not only for prompt detection of ischemia (in seconds), but also for clear differentiation between an arterial occlusion and venous occlusion.

摘要

皮瓣手术是一种广泛应用于整形外科学的复杂手术工具。皮瓣缺血是最危险的并发症之一,无论是在手术过程中还是在患者康复期间,都可能迅速导致组织坏死(皮瓣丧失),并带来严重的医疗和心理后果。如今,床边临床评估仍然是皮瓣监测的金标准,但及时发现皮瓣缺血是一项困难且具有挑战性的任务,因此需要辅助技术来支持皮瓣监测。在这里,我们提出了一种基于漫反射光谱中可见光吸收的新型光学诊断工具的原型,用于非侵入性、连续、实时监测皮瓣。所提出的方法通过监测猪动物模型上诱导的皮瓣缺血情况进行评估。所获得的结果表明,该方法不仅具有快速(在几秒钟内)检测缺血的巨大潜力,而且还可以清楚地区分动脉阻塞和静脉阻塞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc65/10556086/98b47e7bd2e4/41598_2023_44017_Fig1_HTML.jpg

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