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脊髓刺激对鸡胚背阔肌发育过程中代谢的影响。

Effect of spinal cord stimulation on the metabolism of developing latissimus dorsii muscles in chick embryo.

作者信息

Fournier Le Ray C, Renaud D, Le Douarin G H

出版信息

Cell Differ. 1986 Dec;19(4):225-8. doi: 10.1016/0045-6039(86)90098-9.

DOI:10.1016/0045-6039(86)90098-9
PMID:3779847
Abstract

Influence of chronic spinal cord stimulation upon some characteristic enzyme activities of energy metabolism was investigated in slow anterior (ALD) and fast posterior (PLD) latissimus dorsii muscles of the chick embryo. During embryonic life, oxidative metabolism (as evaluated by the activity of malate dehydrogenase (MDH] represents the main energetic pathway in both slow and fast muscles. At the end of embryonic life, an increase in anaerobic (as evaluated by the activity of lactate dehydrogenase (LDH] and creatine phosphokinase (CPK) activities occurs in PLD muscle. Chronic spinal cord stimulation at a low frequency was performed from the 10th day to the 16th day of embryonic development. In ALD, the enzyme activities were unaffected, while in PLD a concomitant decrease in LDH and CPK activities was observed.

摘要

在鸡胚的慢肌前背阔肌(ALD)和快肌后背阔肌(PLD)中,研究了慢性脊髓刺激对能量代谢某些特征性酶活性的影响。在胚胎期,氧化代谢(通过苹果酸脱氢酶(MDH)的活性评估)是慢肌和快肌中的主要能量途径。在胚胎期末期,PLD肌中无氧代谢(通过乳酸脱氢酶(LDH)和肌酸磷酸激酶(CPK)的活性评估)增加。在胚胎发育的第10天至第16天进行了低频慢性脊髓刺激。在ALD中,酶活性未受影响,而在PLD中观察到LDH和CPK活性同时降低。

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Effect of spinal cord stimulation on the metabolism of developing latissimus dorsii muscles in chick embryo.脊髓刺激对鸡胚背阔肌发育过程中代谢的影响。
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引用本文的文献

1
Effects of low and high frequency patterns of stimulation on contractile properties, enzyme activities and myosin light chain accumulation in slow and fast denervated muscles of the chicken.低频和高频刺激模式对鸡慢、快失神经肌肉收缩特性、酶活性及肌球蛋白轻链积累的影响。
Pflugers Arch. 1987 Nov;410(4-5):433-40. doi: 10.1007/BF00586522.