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儿童人群中的脊柱骨样骨瘤:一种管理算法与系统评价

Spinal osteoid osteoma in the pediatric population: A management algorithm and systematic review.

作者信息

Farid Alexander R, Liu David S, Morcos Mary M, Hogue Grant D

机构信息

Harvard Medical School, Boston Children's Hospital, Boston, MA, USA.

Harvard Combined Orthopaedic Residency Program, Boston, MA, USA.

出版信息

J Child Orthop. 2023 Aug 30;17(5):428-441. doi: 10.1177/18632521231192477. eCollection 2023 Oct.

Abstract

PURPOSE

The purpose of this study is to develop an accessible step-wise management algorithm for the management of pediatric spinal osteoid osteomas (OOs) based on a systematic review of the published literature regarding the diagnostic evaluation, treatment, and outcomes following surgical resection.

METHODS

A systematic review of the literature was conducted on PubMed to locate English language studies reporting on the management of pediatric spinal OOs. Data extraction of clinical presentation, management strategies and imaging, and treatment outcomes were performed.

RESULTS

Ten studies reporting on 85 patients under the age of 18 years presenting with OOs were identified. Back pain was the most common presenting symptom, and scoliosis was described in 8 out of 10 studies, and radicular pain in 7 out of 10 studies. Diagnostic, intraoperative, and postoperative assessment included radiographs, computed tomography (CT) scans, magnetic resonance imaging (MRI), bone scans, and frozen section. Treatment options varied, including conservative management, open surgical resection with or without intraoperative imaging, and percutaneous image-guided treatment. All included studies described partial or complete resolution of pain in the immediate postoperative period.

CONCLUSIONS

The proposed algorithm provides a suggested framework for management of pediatric spinal OOs based on the available evidence (levels of evidence: 3, 4). This review of the literature indicated that a step-wise approach should be utilized in the management of pediatric spinal OOs.

摘要

目的

本研究的目的是基于对已发表文献中有关小儿脊柱骨样骨瘤(OOs)的诊断评估、治疗及手术切除后结局的系统评价,制定一种可获取的逐步管理算法。

方法

在PubMed上对文献进行系统评价,以查找关于小儿脊柱OOs管理的英文研究报告。对临床表现、管理策略及影像学检查和治疗结局进行数据提取。

结果

确定了10项报告18岁以下OOs患者的研究,共85例。背痛是最常见的症状,10项研究中有8项描述了脊柱侧弯,10项研究中有7项描述了神经根性疼痛。诊断、术中及术后评估包括X线片、计算机断层扫描(CT)、磁共振成像(MRI)、骨扫描及冰冻切片。治疗选择各异,包括保守治疗、有或无术中成像的开放手术切除以及经皮影像引导治疗。所有纳入研究均描述了术后即刻疼痛部分或完全缓解。

结论

所提出的算法基于现有证据(证据级别:3、4)为小儿脊柱OOs的管理提供了一个建议框架。该文献综述表明,小儿脊柱OOs的管理应采用逐步方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5aa/10549702/8112f0cb24b5/10.1177_18632521231192477-fig1.jpg

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