Key Laboratory of Acupuncture and Neurology of Zhejiang Province, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
The Third School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Medicine (Baltimore). 2023 Oct 6;102(40):e35291. doi: 10.1097/MD.0000000000035291.
Chemogenetics has been widely adopted in Neuroscience. Neuroscience has become a hot research topic for scientists. Therefore, the purpose of this study is to explore the current status and trends in the global application of chemogenetics in neuroscience over the last 14 years via CiteSpace.
Publications related to chemogenetics in neuroscience were retrieved from the Science Citation Index-Extended Web of Science from 2008 to 2021. We used CiteSpace to analyze publications, citations, cited journals, countries, institutions, authors, cited authors, cited references, and keywords.
A total of 947 records were retrieved from 2008 to 2021 on February 21, 2022. The number and rate of publications and citations increased significantly. Journal of Neuroscience was the most cited journal, and BRAIN RES BULL ranked first in the centrality of cited journals. The United States of America (USA) had the highest number of publications among the countries. Takashi Minamoto was the most prolific author and Armbruster BN ranked the first among authors cited. The first article in the frequency ranking of the references cited was published by Roth BL. The keyword of "nucleus accumben (NAc)" had the highest frequency. The top 3 keywords with the strongest citation bursts include "transgenic mice," "cancer," and "blood-brain barrier."
The period 2008 to 2021 has seen a marked increase in research on chemogenetics in neuroscience. The application of chemogenetics is indispensable for research in the field of neuroscience. This bibliometrics study provides the current situation and trend in chemogenetic methods in neuroscience in recent 14 years, which may help researchers to identify the hot topics and frontiers for future studies in this field.
化学生物学在神经科学中得到了广泛的应用。神经科学已成为科学家的热门研究课题。因此，本研究旨在通过 CiteSpace 探索过去 14 年全球神经科学中化学生物学的应用现状和趋势。
从 2008 年至 2021 年，从科学引文索引扩展版 Web of Science 中检索与神经科学中的化学生物学相关的文献。我们使用 CiteSpace 分析出版物、引文、被引期刊、国家、机构、作者、被引作者、被引参考文献和关键词。
共检索到 2008 年至 2021 年 2 月 21 日的 947 条记录。出版物和引文数量和增长率均显著增加。《神经科学杂志》是被引频次最高的期刊，《脑研究公报》在被引期刊的中心度中排名第一。美国在国家中发表的文章数量最多。Takashi Minamoto 是最多产的作者，Armbruster BN 在被引作者中排名第一。参考文献频次排名第一的文章是由 Roth BL 发表的。“伏隔核（NAc）”的关键词出现频次最高。引用率最强的 3 个关键词包括“转基因小鼠”、“癌症”和“血脑屏障”。
2008 年至 2021 年期间，神经科学中化学生物学的研究显著增加。化学生物学的应用对于神经科学领域的研究是不可或缺的。这项文献计量学研究提供了过去 14 年神经科学中化学生物学方法的现状和趋势，这可能有助于研究人员确定该领域未来研究的热点和前沿。
