Suppr超能文献

CONUT 可预测老年胃癌患者腹腔镜辅助根治性胃切除术后的并发症。

CONUT can be a predictor of postoperative complications after laparoscopic-assisted radical gastrectomy for elderly gastric cancer patients.

机构信息

Sir Run Run Shaw Hospital, Affiliated with the Zhejiang University School of Medicine Longyou Campus, Longyou, China.

Department of Medicine, GuangXi Medical College, Nanning, China.

出版信息

Medicine (Baltimore). 2023 Oct 6;102(40):e35424. doi: 10.1097/MD.0000000000035424.

Abstract

Compared with young patients, elderly patients with gastric cancer usually have lower muscle mass, poorer nutritional status, lower immunity, and worse cardiopulmonary function. Therefore, how to improve the prognosis of elderly gastric cancer patients after laparoscopic-assisted radical gastrectomy is the focus and difficulty of clinician. The aim of our study was to investigate the risk factors for postoperative complications of these patients. The data of gastric cancer patients aged ≥ 60 years who underwent laparoscopic-assisted radical gastrectomy were analyzed. Univariate was used to determine the potential risk factors and then multivariate analyses was used to determine the independent risk factors for postoperative complications. Univariate analysis showed that age, preoperative red blood cell (RBC), preoperative albumin (ALB), preoperative C-reactive protein (CRP), preoperative hemoglobin (Hb), preoperative blood transfusion, preoperative lymphocytes, total cholesterol, CRP-to-ALB ratio, controlling nutritional status (CONUT) score, TNM stage were all the potential risk factors for postoperative complications. Binary logistic regression showed that CONUT, age and preoperative RBC were correlated with postoperative complications. For elderly gastric cancer patients after laparoscopic-assisted radical gastrectomy, CONUT, age and preoperative RBC were all the independent risk factors for overall postoperative complications and could be used as reliable indicators for judging the short-term prognosis.

摘要

与年轻患者相比,老年胃癌患者通常肌肉量较低,营养状况较差,免疫力和心肺功能更差。因此,如何提高老年胃癌患者腹腔镜辅助根治性胃切除术后的预后是临床医生关注的焦点和难点。本研究旨在探讨这些患者术后并发症的危险因素。分析了年龄≥60 岁接受腹腔镜辅助根治性胃切除术的胃癌患者的数据。单因素用于确定潜在的危险因素,然后多因素分析用于确定术后并发症的独立危险因素。单因素分析显示,年龄、术前红细胞(RBC)、术前白蛋白(ALB)、术前 C 反应蛋白(CRP)、术前血红蛋白(Hb)、术前输血、术前淋巴细胞、总胆固醇、CRP 与 ALB 比值、营养状况评估(CONUT)评分、TNM 分期均为术后并发症的潜在危险因素。二项逻辑回归显示,CONUT、年龄和术前 RBC 与术后并发症相关。对于接受腹腔镜辅助根治性胃切除术的老年胃癌患者,CONUT、年龄和术前 RBC 均是整体术后并发症的独立危险因素,可作为判断短期预后的可靠指标。

相似文献

3
Sarcopenia is an effective prognostic indicator of postoperative outcomes in laparoscopic-assisted gastrectomy.
Eur J Surg Oncol. 2019 Jun;45(6):1092-1098. doi: 10.1016/j.ejso.2018.09.030. Epub 2019 Feb 6.
6
Effect of nutritional risk on short-term outcomes after laparoscopic-assisted gastrectomy: a prospective study from two centers.
Eur J Gastroenterol Hepatol. 2018 Feb;30(2):136-142. doi: 10.1097/MEG.0000000000001017.

引用本文的文献

1
Preoperative CONUT score predicts postoperative complications in stage I-III gastric cancer patients undergoing curative gastric resections.
Turk J Surg. 2025 Sep 3;41(3):261-269. doi: 10.47717/turkjsurg.2025.2025-7-36. Epub 2025 Sep 1.
6
Using the combined C-reactive protein and controlling nutritional status index for elderly non-small cell lung cancer.
J Thorac Dis. 2024 Jul 30;16(7):4400-4408. doi: 10.21037/jtd-24-435. Epub 2024 Jul 22.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验