Shikh E V, Makhova A A, Dorogun O B, Elizarova E V
I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), 119991, Moscow, Russian Federation.
Vopr Pitan. 2023;92(4):20-28. doi: 10.33029/0042-8833-2023-92-4-20-28. Epub 2023 Aug 14.
Claims that consumption of phytate-rich grains, by definition, worsens mineral status needs to be clarified as new evidence emerges about the role of phytic acids (FA) from whole grains in improving population health outcomes. In this regard, it seems appropriate to draw the attention of practitioners to the need to correct patient's diet in order to prevent non-communicable diseases. of this review was to generalize and analyze the modern data on the role of phytates in human nutrition. . A search for domestic and foreign literature in the bibliographic databases of articles on medical sciences was carried out using the PubMed, MEDLINE and eLibrary search engines. . Deficit of minerals and trace elements in the diet, especially deficiency of iron, calcium, selenium, zinc, iodine, is an urgent public health problem in many countries. Calcium, magnesium, zinc, selenium, and iron deficiencies are associated with impaired immune function and an increased risk of both acute and chronic diseases. Vegan and vegetarian behavior styles with the restriction and exclusion of animal sources of bioavailable minerals and trace elements are gaining more and more popularity in our country. FA is the main storage form of phosphorus in nuts, grains, legumes, and seeds, which satisfies the biosynthesis needs of growing tissues during germination. FA is known as a dietary inhibitor that chelates minerals and trace elements, limiting their bioavailability and reducing their absorption. Pre-treatment methods to reduce phytate levels and increase the nutritional value of diets are fermentation, soaking, and sprouting. Reducing phytate content in plant foods by processing leads to a measurable improvement in mineral status, however, the chelating and antioxidant properties of phytates may be beneficial and their potential in the prevention of cancer, cardiovascular disease, diabetes mellitus and kidney stone formation is currently being studied. . Essential components of a healthy diet are whole whole grains, legumes, vegetables, seeds and nuts, despite the fact that most of them are relatively high in FA. Despite some antinutrient properties, FAs have preventive effects on public health.
随着关于全谷物中植酸对改善人群健康状况作用的新证据不断涌现,那种认为食用富含植酸盐的谷物必然会恶化矿物质状况的说法需要得到澄清。在这方面,提醒从业者注意纠正患者饮食以预防非传染性疾病的必要性似乎是恰当的。本综述的目的是归纳和分析关于植酸盐在人类营养中作用的现代数据。使用PubMed、MEDLINE和eLibrary搜索引擎在医学科学文献的书目数据库中搜索国内外文献。饮食中矿物质和微量元素的缺乏,尤其是铁、钙、硒、锌、碘的缺乏,是许多国家亟待解决的公共卫生问题。钙、镁、锌、硒和铁的缺乏与免疫功能受损以及急慢性疾病风险增加有关。在我国,限制和排除动物来源的生物可利用矿物质和微量元素的纯素食和素食行为方式越来越受欢迎。植酸是坚果、谷物、豆类和种子中磷的主要储存形式,在发芽过程中满足生长组织的生物合成需求。植酸被认为是一种膳食抑制剂,它螯合矿物质和微量元素,限制它们的生物利用度并减少其吸收。降低植酸盐水平并提高饮食营养价值的预处理方法有发酵、浸泡和发芽。通过加工降低植物性食物中的植酸盐含量会使矿物质状况得到显著改善,然而,植酸盐的螯合和抗氧化特性可能是有益的,目前正在研究它们在预防癌症、心血管疾病、糖尿病和肾结石形成方面的潜力。健康饮食的基本组成部分包括全谷物、豆类、蔬菜、种子和坚果,尽管它们中的大多数植酸含量相对较高。尽管植酸有一些抗营养特性,但它们对公众健康有预防作用。