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一名儿科患者萘中毒后出现高铁血红蛋白血症和急性血管内溶血。

Methemoglobinemia and acute ıntravascular hemolysis after naphthalene poisoning in a pediatric patient.

作者信息

Orhan Özhan, Talay Mehmet N

机构信息

Mardin Artuklu University Faculty of Medicine, Turkey.

出版信息

Arch Argent Pediatr. 2024 Apr 1;122(2):e202310095. doi: 10.5546/aap.2023-10095.eng. Epub 2023 Oct 12.

DOI:10.5546/aap.2023-10095.eng
PMID:37801672
Abstract

Poisoning by naphthalene is uncommon in children. It is a type of poisoning brought on by ingesting, inhaling, or coming into touch with naphthalene-containing substances on the skin. Patients typically present with an initial onset of dark brown urine, watery diarrhea, and bile vomit. The signs include fever, tachycardia, hypotension, and low pulse oximetry readings even with oxygen support. Hemolytic anemia, methemoglobinemia, renal failure, and hyperbilirubinemia are all detected in blood tests. Erythrocyte transfusion, ascorbic acid, methylene blue, and N-acetylcysteine (NAC) therapies are provided to inpatients in addition to symptomatic treatment. We present a 23-month-old male patient who developed methemoglobinemia and acute ıntravascular hemolysis, who was followed up in the intensive care unit for five days due to naphthalene intoxication. Although naphthalene poisoning is very rare, it should be known that it has fatal consequences, and more care should be taken in its use and sale.

摘要

萘中毒在儿童中并不常见。它是一种因摄入、吸入或皮肤接触含萘物质而导致的中毒类型。患者通常最初表现为深褐色尿液、水样腹泻和胆汁性呕吐。体征包括发热、心动过速、低血压,即使给予氧气支持,脉搏血氧饱和度读数也较低。血液检查可发现溶血性贫血、高铁血红蛋白血症、肾衰竭和高胆红素血症。除对症治疗外,还会为住院患者提供红细胞输血、抗坏血酸、亚甲蓝和N-乙酰半胱氨酸(NAC)治疗。我们报告一名23个月大的男性患者,他出现了高铁血红蛋白血症和急性血管内溶血,因萘中毒在重症监护病房接受了五天的随访。尽管萘中毒非常罕见,但应该知道它会产生致命后果,在其使用和销售过程中应更加谨慎。

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