Yale School of Medicine, United States.
Loyola University Chicago, United States.
Soc Sci Med. 2023 Nov;336:116257. doi: 10.1016/j.socscimed.2023.116257. Epub 2023 Sep 22.
Appeals to intuitive morality may present a novel approach to addressing vaccine hesitancy.
To better understand the relationship between morality and vaccination by employing Moral Foundations Theory to studies surrounding the HPV vaccination at multiple different levels of decision making.
We employed three different study modalities which examined moralities link to vaccination by employing Moral Foundations Theory. A state-wide ecological study aimed to understand population level trends. Two randomized control interventional studies were then created to understand the effects of Moral Foundations Theory based interventions on both parents of children and individual decision makers.
We demonstrated a negative association at the state level between the purity moral foundations and HPV vaccination rates (β = -.75, SE 0.23; p < .01) and a positive association between loyalty and HPV vaccination rates (β = 0.62 SE 0.24; p < .05). The parental study built upon this by demonstrating negative association between higher moral purity scores and attitudes towards the HPV vaccine and intention to vaccinate their children (β = -0.27 SE 0.07; p < .001). Our final study demonstrated a Moral Foundations Theory based intervention was associated with an increase in the odds of indicating an intention to receive the HPV vaccination (adjusted Odds Ratio (aOR) 2.59, 95% Confidence Interval (CI) 1.62-4.14). This equates to a 20% increase in the predicted probability of the intention to receive an HPV vaccine (39% CI (36%-42%) vs 60% CI (57%-63%).
Together, these studies demonstrate that moral foundations, specifically the purity foundation, appear to have a strong and consistent relationship with HPV vaccination. They also demonstrate the how moral values-based interventions may serve as a novel approach to increase HPV vaccine uptake with potential to be employed to target vaccine hesitancy more broadly.
诉诸直觉道德可能是解决疫苗犹豫的一种新方法。
通过运用道德基础理论（Moral Foundations Theory）在多个不同决策层面研究 HPV 疫苗接种，更好地理解道德与疫苗接种之间的关系。
我们采用了三种不同的研究模式，通过运用道德基础理论（Moral Foundations Theory）研究道德与疫苗接种的关系。一项全州范围的生态研究旨在了解人群水平的趋势。然后，进行了两项随机对照干预研究，以了解基于道德基础理论的干预对儿童父母和个体决策者的影响。
我们在州一级的研究中发现，纯洁道德基础与 HPV 疫苗接种率呈负相关（β=-.75，SE 0.23；p<.01），忠诚道德基础与 HPV 疫苗接种率呈正相关（β=0.62，SE 0.24；p<.05）。父母研究在此基础上进一步表明，更高的道德纯洁评分与对 HPV 疫苗的态度以及为孩子接种疫苗的意愿呈负相关（β=-0.27，SE 0.07；p<.001）。我们的最后一项研究表明，基于道德基础理论的干预与增加表示接种 HPV 疫苗的意愿的几率相关（调整后的优势比（aOR）为 2.59，95%置信区间（CI）为 1.62-4.14）。这相当于接受 HPV 疫苗接种的意愿的预测概率增加了 20%（39%CI（36%-42%）与 60%CI（57%-63%））。
总之，这些研究表明，道德基础，特别是纯洁基础，似乎与 HPV 疫苗接种有很强且一致的关系。它们还表明，基于道德价值观的干预措施可能成为增加 HPV 疫苗接种率的一种新方法，并有潜力更广泛地用于解决疫苗犹豫问题。
