Cameron W I, Moffitt P S, Williams D R
Diabetes Res Clin Pract. 1986 Sep-Oct;2(5):307-14. doi: 10.1016/s0168-8227(86)80008-0.
294 subjects, 89% of the adult Aboriginal population of Bourke and Enngonia, New South Wales, were investigated for diabetes and IGT (impaired glucose tolerance). The prevalence of known diabetes was 9.5%, that of previously unknown diabetes 6.1% and that of IGT 2.4% (all defined according to World Health Organization criteria). A serum glucose value 2 h after 75 g of glucose was found to be an acceptable screening test but not HbA1 due to a large number of false positives. The total prevalence of diabetes (15.6%) was lower than the 19.0% described in the study of Aboriginals in Davenport [Wise et al., Med. J. Aust., 2: 1001-1006, 1970]. However, when these crude prevalences are standardized, the prevalence in Bourke and Enngonia (15.6%) is higher than that calculated for Davenport (11.2%) and higher than that found in a previous report of the Bourke population [Kamien, Med. J. Aust., Spec. Suppl., April: 38-44, 1976]. In contrast to Davenport a large proportion (67%) of diabetic subjects in Bourke were under the age of 50. This may be partly attributable to obesity which, relative to older subjects, was common in young adults in Bourke, particularly men. The consumption of alcohol in this population, though high, was not associated with abnormal glucose tolerance.
对新南威尔士州伯克和恩戈尼亚成年原住民人口的89%(共294名受试者)进行了糖尿病和糖耐量受损(IGT)调查。已知糖尿病的患病率为9.5%,既往未知糖尿病的患病率为6.1%,IGT的患病率为2.4%(均根据世界卫生组织标准定义)。发现口服75克葡萄糖后2小时的血糖值是一种可接受的筛查试验,但糖化血红蛋白(HbA1)由于假阳性数量较多而不适用。糖尿病的总患病率(15.6%)低于达文波特对原住民研究中描述的19.0%[怀斯等人,《澳大利亚医学杂志》,2:1001 - 1006,1970年]。然而,当对这些粗患病率进行标准化后,伯克和恩戈尼亚的患病率(15.6%)高于为达文波特计算的患病率(11.2%),也高于之前关于伯克人群的报告中的患病率[卡米恩,《澳大利亚医学杂志》,特刊增刊,4月:38 - 44,1976年]。与达文波特不同的是,伯克的糖尿病患者中有很大一部分(67%)年龄在50岁以下。这可能部分归因于肥胖,相对于老年受试者,肥胖在伯克的年轻人中很常见,尤其是男性。该人群的酒精消费量虽然很高,但与糖耐量异常无关。