School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan; School of Nursing, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan; Cochrane Taiwan, Taipei Medical University, Taipei, Taiwan; Research Center in Nursing Clinical Practice, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; Department of Nursing, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
Eur J Oncol Nurs. 2023 Dec;67:102424. doi: 10.1016/j.ejon.2023.102424. Epub 2023 Sep 19.
Immersive virtual reality (IVR) shows promise in cancer care, especially for chemotherapy patients. This systematic review and meta-analysis assesses IVR's impact on adult and pediatric cancer patients undergoing chemotherapy.
We searched PubMed, Cochrane Library, Embase, Scopus, Web of Science, and Google Scholar for relevant randomized controlled trials (RCTs). We focused on anxiety, depression, fatigue, pain, and anxiety in adults and pain and anxiety in pediatric patients.
Fifteen trials were included, enrolling 607 adult and 257 pediatric cancer patients. IVR significantly reduced anxiety (SMD = -1.89, 95% CI = -2.93 to -0.85), depression (SMD = -1.85, 95% CI = -3.14 to -0.55), fatigue (SMD = -3.40, 95% CI = -5.54 to -1.26), and systolic blood pressure (MD = -3.54, 95% CI = -6.67 to -0.40) in adults. In pediatric patients, IVR significantly lowered pain (SMD = -1.17, 95% CI = -1.84 to -0.50) and anxiety (SMD = -1.18, 95% CI = -1.77 to -0.59) but not heart rate (MD = 0.48, 95% CI = -2.38 to 3.34).
IVR effectively reduces anxiety, depression, fatigue, systolic blood pressure, pain, and anxiety in cancer patients. More robust RCTs are needed for further IVR research.
沉浸式虚拟现实（IVR）在癌症治疗中具有广阔的应用前景，尤其是在化疗患者中。本系统评价和荟萃分析评估了 IVR 对接受化疗的成年和儿科癌症患者的影响。
我们检索了 PubMed、Cochrane 图书馆、Embase、Scopus、Web of Science 和 Google Scholar 中的相关随机对照试验（RCT）。我们主要关注成年患者的焦虑、抑郁、疲劳、疼痛和焦虑，以及儿科患者的疼痛和焦虑。
纳入了 15 项试验，共纳入了 607 名成年癌症患者和 257 名儿科癌症患者。IVR 显著降低了成年患者的焦虑（SMD=-1.89，95%CI=-2.93 至-0.85）、抑郁（SMD=-1.85，95%CI=-3.14 至-0.55）、疲劳（SMD=-3.40，95%CI=-5.54 至-1.26）和收缩压（MD=-3.54，95%CI=-6.67 至-0.40）。在儿科患者中，IVR 显著降低了疼痛（SMD=-1.17，95%CI=-1.84 至-0.50）和焦虑（SMD=-1.18，95%CI=-1.77 至-0.59），但对心率（MD=0.48，95%CI=-2.38 至 3.34）没有影响。
IVR 可有效降低癌症患者的焦虑、抑郁、疲劳、收缩压、疼痛和焦虑。需要更多的 RCT 来进一步研究 IVR。
