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颈动脉内膜切除术后,监测性双功超声检查促使了干预措施的实施。

Surveillance duplex ultrasound prompted interventions after carotid endarterectomy.

作者信息

Clark Abigail, McMackin Katherine K, Knapp Kristen, Zemela Mark, Tjaden Bruce, Batista Philip, Carpenter Jeffrey P, Lombardi Joseph V

机构信息

Division of Vascular and Endovascular Surgery, Department of Surgery, Cooper University Hospital, Camden, NJ.

Division of Vascular and Endovascular Surgery, Department of Surgery, Cooper University Hospital, Camden, NJ.

出版信息

J Vasc Surg. 2024 Feb;79(2):280-286. doi: 10.1016/j.jvs.2023.10.001. Epub 2023 Oct 5.

DOI:10.1016/j.jvs.2023.10.001
PMID:37804953
Abstract

OBJECTIVE

Current societal guidelines recommend duplex ultrasound (DUS) surveillance beyond 30 days after carotid endarterectomy (CEA) for patients with risk factors for restenosis or who underwent primary closure. However, the appropriate duration of this surveillance has not yet been identified, and the rate at which DUS surveillance prompts intervention is unknown. Multiple calls for decreasing health care spending that does not provide value, including unnecessary testing, have been made. The purpose of this study was to examine the rate of intervention prompted by surveillance DUS on the ipsilateral or contralateral carotid artery after CEA and determine the value of continued surveillance by determining the rate of DUS-prompted intervention.

METHODS

A single-center, retrospective chart review of all patients older than 18 years who had undergone CEA from August 2009 to July 2022 was performed. Patients with at least one postoperative duplex in our Intersocietal Accreditation Council-accredited ultrasound lab were included. Exclusion criteria were patients with incomplete medical charts or patients who underwent a concomitant procedure. The primary end point was return to the operating room for subsequent intervention based on abnormal surveillance DUS findings. Secondary end points were the number of postoperative surveillance duplexes, duration of surveillance, and incidence of perioperative stroke. The study participant data were queried for patients who had a diagnosis of stroke that occurred following their procedure.

RESULTS

A total 767 patients, accounting for 771 procedures, were included in this study, which resulted in 2145 ultrasound scans. A total of 40 (5.2%) patients required 44 subsequent interventions that were prompted by DUS surveillance scans. The average number of ultrasound scans per patient was 2.8 (range: 0-14), and the average duration of surveillance was 26.4 months (range: 0-155 months). Of the 767 patients, 669 (87.2%) had a unilateral CEA. A total of 62 of 767 (8.1%) patients had planned endarterectomies on the contralateral side based on initial imaging, not prompted by interval DUS surveillance scans. Of 767 patients, 28 (3.7%) patients who underwent CEA had a subsequent procedure for progression of contralateral disease, which was prompted by duplex surveillance scans. The average duration between index CEA and intervention on contralateral carotid was 29.57 months (range: 3-81 months). A total of 11 patients, accounting for 12 procedures, underwent a subsequent procedure for restenosis of their ipsilateral carotid, prompted by duplex surveillance scans. The average duration between index CEA and reintervention on the ipsilateral carotid was 17.9 months (range: 4-70 months). Three of 767 (0.4%) patients in total were identified as having a perioperative stroke.

CONCLUSIONS

The overall rate of ipsilateral reintervention after CEA is low. A small percentage of patients will progress their contralateral disease, ultimately requiring surgical intervention. These data suggest that regular duplex surveillance after CEA is warranted for patients with at least moderate contralateral disease; however, the yield is low for ipsilateral restenosis after 36 months based on this single institution study. Further study is needed to better delineate which patients need follow-up to decrease unnecessary testing while still targeting patients most at risk of restenosis or contralateral progression of disease.

摘要

目的

当前社会指南建议,对于有再狭窄风险因素或接受一期缝合的颈动脉内膜切除术(CEA)患者,在术后30天以上进行双功超声(DUS)监测。然而,这种监测的适当持续时间尚未确定,DUS监测促使干预的发生率也未知。人们多次呼吁减少不提供价值的医疗保健支出,包括不必要的检查。本研究的目的是检查CEA术后同侧或对侧颈动脉监测DUS促使干预的发生率,并通过确定DUS促使干预的发生率来确定持续监测的价值。

方法

对2009年8月至2022年7月期间所有接受CEA的18岁以上患者进行单中心回顾性病历审查。纳入在我们经社会间认证委员会认可的超声实验室至少进行过一次术后双功超声检查的患者。排除标准为病历不完整的患者或接受了同期手术的患者。主要终点是基于异常监测DUS结果返回手术室进行后续干预。次要终点是术后监测双功超声检查的次数、监测持续时间和围手术期卒中的发生率。查询研究参与者数据,以获取术后发生卒中诊断的患者。

结果

本研究共纳入767例患者,共进行了771例手术,共进行了2145次超声扫描。共有40例(5.2%)患者因DUS监测扫描需要进行44次后续干预。每位患者的超声扫描平均次数为2.8次(范围:0 - 14次),平均监测持续时间为26.4个月(范围:0 - 155个月)。在767例患者中,669例(87.2%)接受了单侧CEA。767例患者中共有62例(8.1%)基于初始影像学检查计划对侧行内膜切除术,并非由间期DUS监测扫描促使。在767例患者中,28例(3.7%)接受CEA的患者因双功监测扫描促使对侧疾病进展而进行了后续手术。初次CEA与对侧颈动脉干预之间的平均持续时间为29.57个月(范围:3 - 81个月)。共有11例患者,共进行了12例手术,因双功监测扫描促使同侧颈动脉再狭窄而进行了后续手术。初次CEA与同侧颈动脉再次干预之间的平均持续时间为17.9个月(范围:4 - 70个月)。767例患者中共有3例(0.4%)被确定为发生围手术期卒中。

结论

CEA术后同侧再次干预的总体发生率较低。一小部分患者对侧疾病会进展,最终需要手术干预。这些数据表明,对于至少有中度对侧疾病的患者,CEA术后定期双功监测是必要的;然而,基于这项单机构研究,36个月后同侧再狭窄的检出率较低。需要进一步研究以更好地确定哪些患者需要随访,以减少不必要的检查,同时仍针对再狭窄或对侧疾病进展风险最高的患者。

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