Maternal-Fetal Medicine Division, Cam Sakura City Hospital, Health Sciences University Istanbul, İstanbul, Türkiye.
Department of Obstetrics and Gynecology, Istanbul Sisli Etfal Hospital, Health Science University, İstanbul, Türkiye.
Echocardiography. 2023 Nov;40(11):1292-1299. doi: 10.1111/echo.15701. Epub 2023 Oct 8.
Maternal hyperoxygenation (MH) has been studied as a diagnostic tool to evaluate pulmonary vasculature and as a treatment option to improve the growth of fetal left heart in fetuses with left-sided cardiac defects. Chronic maternal hyperoxygenation (CMH) therapy leads to an improvement in fetal pulmonary blood flow resulting in an enhanced venous return to the left heart with increased gestational age. With this manipulation it is anticipated to augment blood flow directed remodeling of the left heart structures and to improve left heart growth spanning from the mitral valve to the aortic isthmus. However, there are concerns about CMH therapy with regard to fetal complications with growth restriction and fetal brain development. Now, with two successful cases we try to discuss this fetal treatment option and related concerns.
母体高氧（MH）已被研究作为一种诊断工具来评估肺血管，并作为一种治疗选择来改善患有左侧心脏缺陷的胎儿的左心生长。慢性母体高氧（CMH）治疗导致胎儿肺血流量增加，导致随着胎龄的增加，静脉回流到左心增加。通过这种操作，可以预期增强血流定向重塑左心结构，并改善从二尖瓣到主动脉峡部的左心生长。然而，CMH 治疗存在胎儿并发症的担忧，包括生长受限和胎儿脑发育。现在，我们通过两个成功的病例来讨论这种胎儿治疗选择和相关问题。
